Basic Information
ID: ALA3227714
Type: Binding
Description: Inhibition of mouse PI3K alpha expressed in insect cells coexpressing p85 subunit assessed as PI(3,4,5)P3 formation using PI(4,5)P2 as substrate by measuring displacement of TAMRA-labeled PI(3,4,5)P3 from Grip1 PH domain after 35 mins by ligand displacement fluorescence polarization assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA3227714
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.45 | 3.42 | 3.42 |
| 425.49 | 2.25 | 2.25 |
| 351.41 | 2.87 | 2.87 |
| 365.44 | 3.33 | 3.33 |
| 381.44 | 2.23 | 2.23 |
| 381.44 | 2.23 | 2.23 |
| 367.41 | 2.10 | 2.10 |
| 353.38 | 1.71 | 1.71 |
| 350.42 | 2.96 | 2.96 |