Basic Information
ID: ALA3231659
Type: Functional
Description: Antisecretory activity in Beagle dog assessed as inhibition of histamine-stimulated gastric acid secretion at 40 mg/kg, po administered 1 hr prior to histamine challenge measured every 30 mins for 90 mins relative to placebo control
Organism: Canis lupus familiaris
Strain: Beagle
Tissue: Stomach
Activity Charts
Bioactivity
Activity Types for Assay ALA3231659
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 217.27 | 0.96 | 0.96 |
| 231.30 | 1.27 | 1.27 |
| 231.30 | 1.27 | 1.27 |
| 231.30 | 1.27 | 1.27 |
| 245.33 | 1.52 | 1.52 |
| 259.35 | 2.08 | 2.08 |
| 273.38 | 2.16 | 2.16 |
| 245.33 | 1.57 | 1.57 |
| 273.38 | 2.08 | 2.08 |
| 353.27 | 3.00 | 3.00 |
| 299.30 | 2.29 | 2.29 |
| 299.30 | 2.29 | 2.29 |
| 261.32 | 1.28 | 1.28 |
| 265.74 | 1.92 | 1.92 |
| 259.35 | 1.88 | 1.88 |
| 202.26 | 2.03 | 2.03 |
| 217.27 | 0.97 | 0.97 |
| 231.30 | 1.23 | 1.23 |
| 273.38 | 2.36 | 2.36 |
| 285.39 | 2.50 | 2.50 |
| 329.49 | 3.92 | 3.92 |
| 301.43 | 3.13 | 3.13 |
| 381.56 | 4.98 | 4.98 |
| 341.50 | 4.06 | 4.06 |
| 259.35 | 1.97 | 1.97 |
| 273.38 | 2.36 | 2.36 |
| 273.38 | 2.35 | 2.35 |
| 387.27 | 1.72 | 1.72 |
| 273.38 | 2.52 | 2.52 |
| 216.28 | 1.56 | 1.56 |
| 247.34 | 1.54 | 1.54 |
| 233.36 | 2.01 | 2.01 |
| 261.39 | 2.94 | 2.94 |