Assay Report Card

Basic Information

ID: ALA3238625

Type: Binding

Description: Inhibition of SARS coronavirus papain-like protease (amino acids 1541 to 1855) expressed in Escherichia coli BL21 (DE3) cells assessed as decrease in AMC release using Z-RLRGG-AMC as substrate by serum shift assay based multimode plate reader analysis in presence of 5 to 20% human serum albumin

Organism: SARS coronavirus

Cell type: BL21-DE3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
416.524.664.66
416.575.125.12
429.564.894.89
390.505.075.07
390.505.075.07
403.534.334.33