Basic Information
ID: ALA3238628
Type: Binding
Description: Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr by FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3238628
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.22 | 1.57 | 1.57 |
| 321.25 | 4.47 | 4.47 |
| 284.79 | 4.47 | 4.47 |
| 321.25 | 4.47 | 4.47 |
| 714.69 | 8.25 | 8.25 |
| 728.72 | 8.64 | 8.64 |
| 728.72 | 8.64 | 8.64 |
| 728.72 | 8.64 | 8.64 |
| 742.74 | 9.03 | 9.03 |
| 756.77 | 9.42 | 9.42 |
| 706.63 | 7.61 | 7.61 |