Basic Information
ID: ALA3239426
Type: Binding
Description: Agonist activity at TGR5 in mouse GLUTag cells assessed as secretion of GLP-1 after 2 hrs by HEK293 cell-based luciferase reporter gene assay in presence of DPP4 inhibitor PKF275 at 600 nM relative to N-(3,5-dichlorophenyl)-N-(1-(2-methoxyphenyl)ethyl)-3-methylisonicotinamide
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3239426
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.56 | 2.69 | 2.69 |
| 577.61 | 5.33 | 5.33 |