Basic Information
ID: ALA3239494
Type: Functional
Description: Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Jurkat
Target: G-protein coupled bile acid receptor 1(ALA5409)
Document: ALA3232835
Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3239494
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 344.85 | 2.71 | 2.71 |
| 344.85 | 2.71 | 2.71 |
| 344.85 | 2.71 | 2.71 |
| 358.87 | 3.01 | 3.01 |
| 324.43 | 2.36 | 2.36 |
| 342.42 | 2.50 | 2.50 |
| 403.32 | 3.12 | 3.12 |
| 324.43 | 2.36 | 2.36 |
| 362.84 | 2.84 | 2.84 |
| 376.86 | 3.15 | 3.15 |
| 343.86 | 3.31 | 3.31 |
| 344.85 | 2.71 | 2.71 |
| 358.87 | 3.01 | 3.01 |
| 357.89 | 3.62 | 3.62 |
| 357.89 | 3.62 | 3.62 |
| 367.43 | 2.37 | 2.37 |
| 403.41 | 2.94 | 2.94 |
| 403.41 | 2.94 | 2.94 |
| 447.59 | 1.98 | 1.98 |
| 501.56 | 2.69 | 2.69 |
| 465.58 | 2.12 | 2.12 |
| 447.59 | 1.98 | 1.98 |
| 501.56 | 2.69 | 2.69 |
| 487.53 | 2.35 | 2.35 |
| 543.59 | 2.46 | 2.46 |
| 502.55 | 2.09 | 2.09 |
| 488.52 | 1.75 | 1.75 |
| 517.56 | 1.87 | 1.87 |
| 501.56 | 2.84 | 2.84 |
| 487.53 | 2.45 | 2.45 |
| 487.53 | 2.45 | 2.45 |
| 473.50 | 2.06 | 2.06 |
| 473.50 | 2.06 | 2.06 |
| 488.52 | 1.84 | 1.84 |
| 530.55 | 3.24 | 3.24 |
| 544.58 | 3.63 | 3.63 |
| 636.68 | 4.62 | 4.62 |
| 608.62 | 3.98 | 3.98 |
| 594.59 | 4.05 | 4.05 |
| 608.62 | 4.40 | 4.40 |
| 571.56 | 5.34 | 5.34 |
| 577.61 | 5.33 | 5.33 |