Basic Information
ID: ALA3239920
Type: Binding
Description: Inhibition of SARS coronavirus papain-like protease (amino acids 1541 to 1855) expressed in Escherichia coli BL21 (DE3) cells assessed as decrease in AMC release using Z-RLRGG-AMC as substrate by multimode plate reader analysis
Organism: SARS coronavirus
Cell type: BL21-DE3
Activity Charts
Bioactivity
Activity Types for Assay ALA3239920
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.52 | 4.66 | 4.66 |
| 430.55 | 5.05 | 5.05 |
| 432.52 | 3.63 | 3.63 |
| 446.55 | 4.28 | 4.28 |
| 492.62 | 5.88 | 5.88 |
| 372.51 | 4.93 | 4.93 |
| 386.54 | 5.49 | 5.49 |
| 386.54 | 5.49 | 5.49 |
| 416.57 | 5.12 | 5.12 |
| 416.57 | 5.12 | 5.12 |
| 400.57 | 5.49 | 5.49 |
| 429.56 | 4.29 | 4.29 |
| 429.56 | 4.29 | 4.29 |
| 429.56 | 4.89 | 4.89 |
| 429.56 | 4.89 | 4.89 |
| 443.59 | 4.57 | 4.57 |
| 406.96 | 5.58 | 5.58 |
| 406.96 | 5.58 | 5.58 |
| 408.49 | 5.21 | 5.21 |
| 390.50 | 5.07 | 5.07 |
| 390.50 | 5.07 | 5.07 |
| 391.49 | 4.46 | 4.46 |
| 391.49 | 4.46 | 4.46 |
| 391.49 | 4.46 | 4.46 |
| 391.49 | 4.46 | 4.46 |
| 373.50 | 4.32 | 4.32 |
| 373.50 | 4.32 | 4.32 |
| 403.53 | 4.33 | 4.33 |
| 420.98 | 5.63 | 5.63 |
| 404.53 | 5.11 | 5.11 |
| 416.54 | 5.38 | 5.38 |