Basic Information
ID: ALA3240701
Type: Binding
Description: Inhibition of biotin-tagged human GKRP/fluorescein-tagged GK interaction preincubated for 20 mins prior to GK addition measured after 2 to 4 hrs by AlphaScreen assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Glucokinase regulatory protein(ALA1075152)
Document: ALA3232863
Inhibition of biotin-tagged human GKRP/fluorescein-tagged GK interaction preincubated for 20 mins prior to GK addition measured after 2 to 4 hrs by AlphaScreen assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3240701
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 522.47 | 2.88 | 2.88 |
| 468.50 | 2.34 | 2.34 |
| 356.45 | 1.57 | 1.57 |
| 452.50 | 3.23 | 3.23 |
| 484.50 | 1.31 | 1.31 |
| 484.50 | 1.31 | 1.31 |
| 483.52 | 1.28 | 1.28 |
| 483.52 | 1.28 | 1.28 |
| 493.51 | 2.23 | 2.23 |
| 498.53 | 1.96 | 1.96 |
| 492.52 | 2.34 | 2.34 |
| 506.55 | 2.73 | 2.73 |
| 398.49 | 1.77 | 1.77 |
| 413.50 | 0.93 | 0.93 |
| 418.54 | 1.30 | 1.30 |
| 434.54 | 0.97 | 0.97 |
| 435.53 | 0.21 | 0.21 |
| 449.56 | 0.47 | 0.47 |
| 475.60 | 1.01 | 1.01 |
| 477.61 | 1.25 | 1.25 |
| 489.62 | 1.25 | 1.25 |
| 511.63 | 2.37 | 2.37 |
| 433.56 | 1.60 | 1.60 |
| 459.60 | 2.13 | 2.13 |
| 487.53 | 2.49 | 2.49 |
| 487.53 | 2.49 | 2.49 |
| 487.53 | 2.49 | 2.49 |
| 501.56 | 2.54 | 2.54 |
| 469.49 | 1.73 | 1.73 |
| 469.49 | 1.73 | 1.73 |
| 469.49 | 1.73 | 1.73 |
| 469.49 | 1.73 | 1.73 |
| 523.46 | 2.27 | 2.27 |
| 524.45 | 1.67 | 1.67 |
| 450.55 | -0.13 | -0.13 |
| 485.49 | 0.70 | 0.70 |
| 485.49 | 0.70 | 0.70 |
| 485.49 | 0.70 | 0.70 |
| 529.49 | 2.34 | 2.34 |
| 475.52 | 1.79 | 1.79 |