Assay Report Card

Basic Information

ID: ALA3240837

Type: Binding

Description: Inhibition of NorA in fluoroquinolone-resistant Staphylococcus aureus 1199B assessed as potentiation of 4 ug/ml of ciprofloxacin MIC at 100 ug/ml after 24 hrs by microdilution method

Organism: Staphylococcus aureus

Strain: 1199B

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
173.171.931.93
107.110.890.89
157.172.052.05
144.172.552.55
122.121.381.38
94.111.391.39
123.110.780.78
106.121.501.50
200.83
151.96
121.93
608.694.174.17
165.94
128.562.052.05
172.182.542.54
201.022.152.15
156.572.042.04
171.99
127.96
173.012.152.15
95.100.790.79
139.92
198.03
140.91
156.38
140.572.152.15
157.561.431.43
228.06
156.182.652.65
157.36
140.91
147.93
191.81
175.35
182.38
187.39
191.81
323.24
357.69
341.23
337.27
402.14
357.69
341.23
348.25
392.13
375.68
382.70
387.71
122.92
201.82
157.36
140.91
152.95
166.97
229.04
169.01
147.93
216.00
250.45
201.82
157.36
367.30
429.37
357.69
341.23
357.69
402.14
402.14
369.34
348.25
341.23
353.27
172.98
185.00
171.39
222.05
250.45
215.84
216.00
250.45
229.04
169.01
152.95
166.97
369.34
428.38
392.13
436.58
420.13
371.71
422.38
214.03
193.99
179.03
149.99
181.98
170.40
217.94
184.39
350.31
394.32
186.02
211.03
156.01
125.92
298.15
208.07
242.51
374.25
211.09
326.23
298.17
367.37
161.96
344.22
374.37
300.17
286.14
202.011.541.54
171.581.741.74
170.592.352.35
213.242.472.47
185.022.262.26
174.001.551.55
129.551.441.44
143.571.751.75
145.161.941.94
142.592.352.35
162.92
215.252.152.15
392.13
191.81
236.26
219.81