Basic Information
ID: ALA3242135
Type: Binding
Description: Inhibition of human recombinant BBOX expressed in Saccharomyces cerevisiae AH22 assessed as formation of carnitine from gamma-butyrobetaine preincubated for 15 mins measured after 30 mins by UPLC-MS/MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3242135
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 195.28 | 0.02 | 0.02 |
| 146.19 | -1.66 | -1.66 |
| 159.23 | -0.39 | -0.39 |
| 173.26 | 0.00 | 0.00 |
| 175.23 | -1.41 | -1.41 |
| 187.28 | 0.39 | 0.39 |
| 221.30 | 0.79 | 0.79 |
| 171.24 | -0.24 | -0.24 |
| 185.27 | 0.15 | 0.15 |
| 199.29 | 0.54 | 0.54 |
| 185.27 | 0.00 | 0.00 |
| 199.29 | 0.39 | 0.39 |
| 213.68 | 0.90 | 0.90 |
| 193.67 | 0.95 | 0.95 |
| 207.70 | 1.09 | 1.09 |
| 173.26 | 0.00 | 0.00 |
| 171.24 | -0.22 | -0.22 |
| 173.26 | 0.00 | 0.00 |
| 169.22 | -0.77 | -0.77 |
| 179.65 | -0.21 | -0.21 |
| 224.10 | -0.05 | -0.05 |
| 271.10 | -0.01 | -0.01 |
| 175.23 | -0.80 | -0.80 |
| 157.21 | -0.26 | -0.26 |
| 230.13 | 1.17 | 1.17 |
| 274.59 | 1.32 | 1.32 |
| 185.27 | 0.00 | 0.00 |
| 159.23 | -0.39 | -0.39 |
| 216.11 | 0.77 | 0.77 |
| 143.19 | -1.00 | -1.00 |
| 181.26 | -0.37 | -0.37 |
| 217.63 | 0.26 | 0.26 |
| 165.17 | -0.08 | -0.08 |
| 179.20 | 0.31 | 0.31 |
| 205.69 | -0.16 | -0.16 |
| 159.23 | -0.39 | -0.39 |
| 264.30 | -0.61 | -0.61 |
| 160.22 | -1.27 | -1.27 |
| 172.23 | -1.11 | -1.11 |
| 174.24 | -0.88 | -0.88 |
| 176.22 | -2.30 | -2.30 |
| 158.20 | -1.15 | -1.15 |
| 275.57 | 0.28 | 0.28 |
| 251.12 | -0.32 | -0.32 |
| 160.22 | -1.32 | -1.32 |
| 174.24 | -0.93 | -0.93 |
| 188.27 | -0.54 | -0.54 |
| 174.24 | -0.93 | -0.93 |
| 210.71 | 0.45 | 0.45 |
| 175.23 | -2.33 | -2.33 |
| 182.25 | -1.26 | -1.26 |
| 310.07 | -0.63 | -0.63 |