Basic Information
ID: ALA3242260
Type: Binding
Description: Inhibition of HSP90 in HEK cells expressing full-length mHtt Q73 gene assessed as reduction of mHtt level after 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Heat shock protein HSP 90-beta(ALA4303)
Document: ALA3232825
Inhibition of HSP90 in HEK cells expressing full-length mHtt Q73 gene assessed as reduction of mHtt level after 24 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3242260
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.55 | 3.06 | 3.06 |
| 436.56 | 2.92 | 2.92 |
| 434.58 | 4.07 | 4.07 |
| 420.56 | 3.54 | 3.54 |
| 424.55 | 2.78 | 2.78 |
| 466.65 | 4.03 | 4.03 |
| 408.55 | 3.54 | 3.54 |
| 406.53 | 3.29 | 3.29 |
| 430.50 | 3.40 | 3.40 |
| 450.58 | 3.17 | 3.17 |
| 408.55 | 3.54 | 3.54 |
| 436.60 | 4.18 | 4.18 |
| 434.58 | 3.73 | 3.73 |
| 363.46 | 2.86 | 2.86 |
| 377.49 | 2.91 | 2.91 |
| 391.52 | 3.30 | 3.30 |
| 419.57 | 4.06 | 4.06 |
| 433.60 | 4.10 | 4.10 |
| 421.54 | 3.81 | 3.81 |
| 378.52 | 4.43 | 4.43 |
| 390.53 | 4.88 | 4.88 |
| 404.55 | 5.27 | 5.27 |
| 406.53 | 4.12 | 4.12 |
| 376.50 | 4.49 | 4.49 |
| 378.52 | 4.57 | 4.57 |
| 378.52 | 4.52 | 4.52 |
| 412.53 | 4.82 | 4.82 |
| 398.51 | 4.89 | 4.89 |
| 416.50 | 5.03 | 5.03 |
| 416.50 | 5.03 | 5.03 |
| 428.53 | 4.90 | 4.90 |