Irreversible inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate prei...

Basic Information

ID: ALA3256793

Type: Binding

Description: Irreversible inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate preincubated at 4 uM for 12 mins in absence of co-factor

Format: BAO_0000357

Organism: Lacticaseibacillus casei

Target:  Thymidylate synthase(ALA5328)

Document:  ALA3244226

Irreversible inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate preincubated at 4 uM for 12 mins in absence of co-factor: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
333.19-1.83-1.83