Basic Information
ID: ALA3259253
Type: Binding
Description: Inhibition of HMG-coA reductase in CD rat liver microsomal-cytosol fraction assessed as inhibition of total lipid synthesis using [2-14C]acetate as substrate after 90 mins by scintillation counting analysis
Organism: Rattus norvegicus
Strain: CD
Activity Charts
Bioactivity
Activity Types for Assay ALA3259253
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 268.36 | 4.40 | 4.40 |
| 282.34 | 4.04 | 4.04 |
| 298.34 | 4.16 | 4.16 |
| 314.41 | 4.52 | 4.52 |
| 296.32 | 4.27 | 4.27 |
| 312.39 | 4.74 | 4.74 |
| 308.38 | 4.14 | 4.14 |
| 284.36 | 4.52 | 4.52 |
| 300.42 | 4.88 | 4.88 |
| 332.42 | 3.56 | 3.56 |
| 282.34 | 4.63 | 4.63 |
| 298.41 | 5.10 | 5.10 |
| 330.41 | 3.54 | 3.54 |
| 294.39 | 4.50 | 4.50 |
| 236.63 | 2.58 | 2.58 |