Assay Report Card

Basic Information

ID: ALA3266687

Type: Binding

Description: Binding affinity to supercoiled pHOT-1 DNA assessed as unwinding of DNA helix by measuring shift of negative to positive supercoiled pHOT-1 at 10 to 150 uM treated 15 mins prior to Escherichia coli topoisomerase 1 addition for 30 mins by agarose gel electrophoresis

Organism: Not specified

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
522.033.103.10