Basic Information
ID: ALA3266887
Type: Binding
Description: Binding affinity to His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of MCL1-N-terminal biotin-labeled BIM BH3 peptide interaction after 30 mins by surface plasmon resonance analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3266887
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 468.35 | 4.29 | 4.29 |
| 419.48 | 3.53 | 3.53 |
| 423.90 | 4.18 | 4.18 |
| 417.51 | 4.09 | 4.09 |
| 389.45 | 3.52 | 3.52 |
| 403.48 | 3.83 | 3.83 |
| 407.44 | 3.66 | 3.66 |
| 395.48 | 3.58 | 3.58 |
| 431.54 | 4.65 | 4.65 |
| 439.51 | 4.68 | 4.68 |
| 505.58 | 4.94 | 4.94 |
| 453.54 | 5.07 | 5.07 |
| 453.54 | 5.07 | 5.07 |
| 482.38 | 4.59 | 4.59 |
| 496.40 | 4.68 | 4.68 |
| 481.39 | 3.99 | 3.99 |
| 479.58 | 5.49 | 5.49 |
| 479.58 | 5.49 | 5.49 |
| 464.38 | 4.73 | 4.73 |
| 510.39 | 4.51 | 4.51 |
| 327.38 | 2.09 | 2.09 |
| 445.56 | 4.82 | 4.82 |
| 468.35 | 4.29 | 4.29 |
| 468.35 | 4.29 | 4.29 |
| 445.54 | 4.74 | 4.74 |
| 465.55 | 5.19 | 5.19 |
| 465.55 | 5.19 | 5.19 |
| 465.55 | 5.19 | 5.19 |
| 500.00 | 5.84 | 5.84 |
| 501.53 | 5.47 | 5.47 |
| 481.55 | 5.32 | 5.32 |
| 499.54 | 5.45 | 5.45 |
| 473.58 | 3.20 | 3.20 |
| 418.29 | 3.13 | 3.13 |
| 432.30 | 4.74 | 4.74 |
| 437.93 | 4.32 | 4.32 |
| 403.48 | 3.20 | 3.20 |
| 401.87 | 4.56 | 4.56 |
| 367.43 | 3.90 | 3.90 |
| 299.35 | 3.35 | 3.35 |
| 466.42 | 6.00 | 6.00 |
| 482.38 | 4.37 | 4.37 |
| 467.37 | 3.69 | 3.69 |
| 436.33 | 4.03 | 4.03 |
| 450.35 | 4.42 | 4.42 |
| 492.38 | 3.91 | 3.91 |