Basic Information
ID: ALA3268063
Type: Binding
Description: Inhibition of N-terminal GST-tagged human recombinant PDE10A assessed as substrate hydrolysis using [3H]cAMP as substrate after 30 mins by two-step radiometric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3268063
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.46 | 5.28 | 5.28 |
| 460.46 | 6.30 | 6.30 |
| 384.41 | 4.90 | 4.90 |
| 366.42 | 4.76 | 4.76 |
| 367.41 | 4.16 | 4.16 |
| 368.40 | 3.55 | 3.55 |
| 384.41 | 4.90 | 4.90 |
| 368.40 | 3.55 | 3.55 |
| 382.43 | 3.60 | 3.60 |
| 398.44 | 4.94 | 4.94 |
| 414.90 | 5.46 | 5.46 |
| 381.44 | 4.20 | 4.20 |
| 382.43 | 3.60 | 3.60 |
| 397.45 | 5.55 | 5.55 |
| 413.91 | 6.06 | 6.06 |
| 380.45 | 4.81 | 4.81 |
| 381.44 | 4.20 | 4.20 |
| 412.47 | 5.33 | 5.33 |
| 395.47 | 4.59 | 4.59 |
| 402.50 | 3.97 | 3.97 |
| 407.48 | 4.69 | 4.69 |
| 417.42 | 5.06 | 5.06 |