Basic Information
ID: ALA3269583
Type: Binding
Description: Inhibition of human recombinant COX-2 expressed in insect cell system using arachidonic acid as substrate assessed as reduction of PGG2 to PGH2 incubated for 1 min prior to substrate addition measured after 25 secs by chromogenic assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3269583
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.51 | 3.51 |
| 296.32 | 4.71 | 4.71 |
| 310.35 | 5.02 | 5.02 |
| 310.35 | 5.02 | 5.02 |
| 326.35 | 4.72 | 4.72 |
| 358.39 | 6.07 | 6.07 |
| 372.42 | 6.38 | 6.38 |
| 372.42 | 6.38 | 6.38 |
| 297.31 | 4.11 | 4.11 |
| 346.38 | 5.86 | 5.86 |