Assay Report Card

Basic Information

ID: ALA3271206

Type: Binding

Description: Inhibition of Isoleucine-tRNA synthetase in wild type Escherichia coli S30 cell extract assessed as inhibition of [C14]isoleucine incorporation in tRNA under in vitro aminoacylation conditions at 3.13 uM by liquid scintillation counting

Organism: Escherichia coli

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
459.49-2.22-2.22
487.49-0.69-0.69
475.48-2.93-2.93
460.47-2.10-2.10
435.46-2.80-2.80
436.44-3.09-3.09
457.51-1.01-1.01