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Antagonist activity at beta-1 adrenergic receptor in spontaneously beating guinea pig right atrium assessed as inhibition of isoprenaline-induced posi...

Basic Information

ID: ALA3280057

Type: Binding

Description: Antagonist activity at beta-1 adrenergic receptor in spontaneously beating guinea pig right atrium assessed as inhibition of isoprenaline-induced positive chronotropic effect preincubated for 30 mins followed by isoprenaline challenge in presence of ascorbic acid

Format: BAO_0000357

Organism: Cavia porcellus

Tissue: Cardiac atrium

Target:  Beta-1 adrenergic receptor(ALA5471)

Document:  ALA3271989

Antagonist activity at beta-1 adrenergic receptor in spontaneously beating guinea pig right atrium assessed as inhibition of isoprenaline-induced positive chronotropic effect preincubated for 30 mins followed by isoprenaline challenge in presence of ascorbic acid: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
272.781.401.40
286.801.791.79
286.801.791.79
300.832.182.18
411.374.054.05
298.811.711.71
312.842.102.10
312.842.102.10
406.482.492.49
434.962.952.95
416.472.942.94
348.872.812.81
362.903.203.20
495.532.662.66
366.411.271.27
376.883.173.17
346.862.792.79
360.893.193.19
436.984.414.41
405.883.093.09
518.684.714.71
519.393.953.95
519.393.953.95
395.333.843.84
531.563.143.14
393.922.772.77
335.282.832.83
394.472.482.48
330.862.182.18
345.832.082.08
459.342.942.94
369.421.761.76
408.502.742.74
422.523.303.30
379.412.052.05
362.921.911.91
378.921.581.58
318.822.322.32
346.922.902.90
376.933.843.84
437.492.132.13
343.381.881.88
438.522.962.96
443.502.222.22
407.961.431.43
394.472.482.48
396.441.881.88
410.472.182.18
414.892.832.83
394.472.482.48
436.512.742.74
369.723.483.48
360.882.192.19
449.333.483.48
440.492.192.19