Basic Information
ID: ALA3280213
Type: Binding
Description: Irreversible inhibition of alpha adrenergic receptor in rat vas deferens assessed as inhibition of NE-induced contractions at 2 x 10' -5 M after 30 mins relative to N1,N1'-(2,2'-disulfanediylbis(ethane-2,1-diyl))dioctane-1,8-diamine tetrahydrochloride
Organism: Rattus norvegicus
Tissue: Vas deferens
Activity Charts
Bioactivity
Activity Types for Assay ALA3280213
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 562.89 | 5.48 | 5.48 |
| 651.52 | 8.42 | 8.42 |
| 623.46 | 7.64 | 7.64 |
| 595.41 | 6.86 | 6.86 |
| 627.41 | 6.26 | 6.26 |
| 627.41 | 6.26 | 6.26 |
| 679.48 | 7.38 | 7.38 |
| 655.46 | 7.04 | 7.04 |
| 709.03 | 6.95 | 6.95 |
| 683.51 | 7.83 | 7.83 |
| 655.46 | 7.04 | 7.04 |
| 627.41 | 6.26 | 6.26 |
| 595.41 | 7.03 | 7.03 |
| 567.35 | 6.25 | 6.25 |
| 524.84 | 4.83 | 4.83 |
| 555.43 | 7.27 | 7.27 |
| 499.32 | 5.71 | 5.71 |
| 471.27 | 4.93 | 4.93 |
| 415.16 | 3.37 | 3.37 |
| 387.10 | 2.59 | 2.59 |
| 322.59 | 1.81 | 1.81 |
| 636.24 | 7.55 | 7.55 |
| 664.30 | 8.33 | 8.33 |
| 687.46 | 6.28 | 6.28 |
| 687.46 | 6.28 | 6.28 |
| 687.46 | 6.28 | 6.28 |
| 687.46 | 6.28 | 6.28 |
| 687.46 | 6.28 | 6.28 |
| 675.80 | 5.07 | 5.07 |
| 705.13 | 8.86 | 8.86 |
| 733.19 | 9.64 | 9.64 |