Assay Report Card

Basic Information

ID: ALA3280214

Type: Binding

Description: Irreversible inhibition of alpha adrenergic receptor in rat vas deferens assessed as inhibition of NE-induced contractions at 2 x 10' -5 M after 30 mins relative to [N,N'-bis(o-methoxybenzylamino-n-hexyl)cystamine

Organism: Rattus norvegicus

Tissue: Vas deferens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
562.895.485.48
651.528.428.42
623.467.647.64
595.416.866.86
627.416.266.26
627.416.266.26
679.487.387.38
655.467.047.04
709.036.956.95
683.517.837.83
655.467.047.04
595.417.037.03
567.356.256.25
524.844.834.83
555.437.277.27
499.325.715.71
471.274.934.93
443.214.154.15
415.163.373.37
387.102.592.59
322.591.811.81
636.247.557.55
664.308.338.33
687.466.286.28
687.466.286.28
687.466.286.28
687.466.286.28
687.466.286.28
675.805.075.07
705.138.868.86
733.199.649.64