Assay Report Card

Basic Information

ID: ALA3283307

Type: Functional

Description: Hypotensive activity in po dosed spontaneously hypertensive Wistar-Okamoto rat assessed as dose required to cause 30 mmHg fall of blood pressure administered for 5 days

Organism: Rattus norvegicus

Strain: Wistar-Okamoto

Tissue: Blood

Activity Charts

Bioactivity

Activity Types for Assay ALA3283307

MED

Total(121)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
231.30	2.11	2.11
289.41	3.61	3.61
217.28	1.72	1.72
231.30	1.97	1.97
245.33	2.35	2.35
259.36	2.89	2.89
245.33	2.50	2.50
273.38	3.13	3.13
259.36	2.74	2.74
265.32	2.16	2.16
265.32	2.68	2.68
259.36	2.74	2.74
217.28	1.72	1.72
243.31	2.25	2.25
229.29	1.86	1.86
201.23	1.08	1.08
231.30	2.11	2.11
245.33	2.50	2.50
259.36	2.89	2.89
237.27	2.25	2.25
259.36	2.74	2.74
259.36	2.74	2.74
203.25	1.33	1.33
215.26	1.50	1.50
265.32	2.16	2.16
245.33	2.50	2.50
245.33	2.35	2.35
251.72	2.37	2.37
217.28	1.72	1.72
245.33	2.35	2.35
231.30	2.11	2.11
243.31	2.25	2.25
247.30	1.73	1.73
245.33	2.35	2.35
251.29	2.12	2.12
231.30	1.97	1.97
273.38	3.03	3.03
259.36	2.45	2.45
277.33	1.55	1.55
231.30	2.11	2.11
217.28	1.72	1.72
271.37	3.03	3.03
251.72	2.37	2.37
259.36	2.89	2.89
245.33	2.34	2.34
231.30	1.97	1.97
259.36	2.60	2.60
273.38	3.13	3.13
229.29	1.86	1.86
273.38	3.14	3.14
217.28	1.58	1.58
231.30	2.11	2.11
217.28	1.72	1.72
296.17	2.48	2.48
229.29	1.63	1.63
203.25	1.33	1.33
175.20	0.55	0.55
265.32	2.87	2.87
237.27	2.25	2.25
245.29	1.10	1.10
251.29	2.12	2.12
241.25	1.71	1.71
260.35	1.26	1.26
233.28	0.96	0.96
243.31	2.25	2.25
255.32	2.11	2.11
229.29	1.72	1.72
259.36	2.60	2.60
245.33	2.35	2.35
245.33	2.35	2.35
286.17	3.03	3.03
161.17	0.50	0.50
244.34	2.96	2.96
245.33	2.35	2.35
154.22	0.56	0.56
295.39	2.89	2.89
273.38	3.13	3.13
295.39	2.89	2.89
279.35	2.86	2.86
247.30	1.35	1.35
373.24	1.54	1.54
235.29	1.93	1.93
263.35	2.56	2.56
248.33	1.85	1.85
248.33	1.67	1.67
268.75	2.02	2.02
330.82	3.38	3.38
344.85	3.77	3.77
267.34	2.87	2.87
295.39	3.57	3.57
208.26	1.63	1.63
222.29	2.02	2.02
222.29	2.02	2.02
222.29	1.80	1.80
278.36	2.78	2.78
249.32	1.71	1.71
234.30	1.78	1.78
302.30	2.72	2.72
369.54	2.99	2.99
360.48	3.33	3.33
284.37	2.75	2.75
320.83	2.75	2.75
277.33	1.98	1.98
287.37	2.61	2.61
231.30	1.40	1.40
231.30	1.40	1.40
263.35	1.79	1.79
259.36	2.03	2.03
245.33	1.44	1.44
230.31	2.71	2.71
244.34	2.94	2.94
258.37	3.33	3.33
285.18	3.63	3.63
274.37	3.11	3.11
260.34	2.72	2.72
232.29	2.03	2.03
259.36	2.39	2.39
273.38	2.78	2.78
273.34	2.28	2.28
239.37	1.14	1.14
223.32	0.46	0.46