Basic Information
ID: ALA3292468
Type: Binding
Description: Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysis
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3292468
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.88 | 1.84 | 1.84 |
| 421.84 | -0.29 | -0.29 |
| 456.28 | 0.37 | 0.37 |
| 500.73 | 0.48 | 0.48 |
| 435.86 | 0.02 | 0.02 |
| 451.86 | -0.80 | -0.80 |
| 439.83 | -0.15 | -0.15 |
| 489.83 | 0.73 | 0.73 |
| 456.28 | 0.37 | 0.37 |
| 435.86 | 0.02 | 0.02 |
| 489.83 | 0.73 | 0.73 |
| 451.86 | -0.28 | -0.28 |
| 519.86 | 0.65 | 0.65 |
| 435.86 | 0.02 | 0.02 |
| 456.28 | 0.37 | 0.37 |
| 439.83 | -0.15 | -0.15 |
| 470.31 | 0.67 | 0.67 |
| 705.21 | 5.21 | 5.21 |
| 504.97 | 1.62 | 1.62 |
| 490.94 | 1.23 | 1.23 |
| 504.97 | 1.62 | 1.62 |
| 476.91 | 0.84 | 0.84 |