Basic Information
ID: ALA3292499
Type: Binding
Description: Inhibition of TPH-1-mediated serotonin biosynthesis in rat RBL2H3 cells at 10 uM after 48 hrs by RP-HPLC analysis relative to control
Organism: Rattus norvegicus
Cell type: RBL-2H3
Activity Charts
Bioactivity
Activity Types for Assay ALA3292499
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.09 | 7.09 |
| 498.75 | 7.66 | 7.66 |
| 659.95 | 8.48 | 8.48 |
| 478.72 | 7.17 | 7.17 |
| 581.88 | 7.92 | 7.92 |
| 615.90 | 8.11 | 8.11 |
| 583.85 | 7.26 | 7.26 |
| 539.80 | 6.89 | 6.89 |
| 625.94 | 8.28 | 8.28 |
| 562.24 | 9.58 | 9.58 |
| 647.34 | 9.17 | 9.17 |
| 689.43 | 10.20 | 10.20 |
| 723.44 | 10.39 | 10.39 |
| 606.69 | 9.69 | 9.69 |
| 691.80 | 9.28 | 9.28 |
| 733.88 | 10.31 | 10.31 |
| 767.89 | 10.50 | 10.50 |
| 609.68 | 9.69 | 9.69 |
| 694.79 | 9.29 | 9.29 |
| 736.87 | 10.31 | 10.31 |
| 770.89 | 10.51 | 10.51 |
| 540.79 | 8.39 | 8.39 |
| 625.90 | 7.98 | 7.98 |
| 667.98 | 9.01 | 9.01 |
| 702.00 | 9.20 | 9.20 |
| 671.99 | 8.62 | 8.62 |
| 713.07 | 10.08 | 10.08 |
| 741.12 | 10.72 | 10.72 |
| 651.00 | 8.90 | 8.90 |
| 666.99 | 8.14 | 8.14 |
| 563.83 | 6.76 | 6.76 |
| 605.91 | 7.78 | 7.78 |
| 639.93 | 7.98 | 7.98 |
| 554.82 | 8.63 | 8.63 |
| 639.93 | 8.22 | 8.22 |
| 682.01 | 9.25 | 9.25 |
| 716.02 | 9.44 | 9.44 |
| 572.81 | 8.77 | 8.77 |
| 657.92 | 8.36 | 8.36 |
| 700.00 | 9.39 | 9.39 |
| 734.01 | 9.58 | 9.58 |
| 479.71 | 7.43 | 7.43 |
| 564.81 | 7.03 | 7.03 |
| 606.89 | 8.05 | 8.05 |
| 640.91 | 8.25 | 8.25 |
| 477.69 | 6.97 | 6.97 |
| 562.80 | 6.56 | 6.56 |
| 604.88 | 7.59 | 7.59 |
| 638.89 | 7.78 | 7.78 |
| 490.73 | 7.23 | 7.23 |
| 575.84 | 6.83 | 6.83 |
| 617.92 | 7.85 | 7.85 |
| 651.94 | 8.05 | 8.05 |