Basic Information
ID: ALA3293516
Type: Binding
Description: Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3293516
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 424.49 | 5.27 | 5.27 |
| 444.52 | 4.89 | 4.89 |
| 308.34 | 2.96 | 2.96 |
| 412.53 | 5.56 | 5.56 |
| 438.56 | 6.09 | 6.09 |
| 414.50 | 4.95 | 4.95 |
| 440.54 | 5.49 | 5.49 |
| 398.50 | 5.47 | 5.47 |
| 424.54 | 6.00 | 6.00 |
| 400.47 | 4.87 | 4.87 |
| 426.51 | 5.40 | 5.40 |
| 398.50 | 5.47 | 5.47 |
| 424.54 | 6.00 | 6.00 |
| 400.47 | 4.87 | 4.87 |
| 426.51 | 5.40 | 5.40 |
| 398.50 | 5.47 | 5.47 |
| 424.54 | 6.00 | 6.00 |
| 400.47 | 4.87 | 4.87 |
| 426.51 | 5.40 | 5.40 |
| 432.94 | 6.12 | 6.12 |
| 458.98 | 6.66 | 6.66 |
| 434.92 | 5.52 | 5.52 |
| 460.95 | 6.05 | 6.05 |
| 416.49 | 5.61 | 5.61 |
| 442.53 | 6.14 | 6.14 |
| 418.46 | 5.00 | 5.00 |
| 444.50 | 5.54 | 5.54 |
| 414.50 | 5.17 | 5.17 |
| 440.54 | 5.71 | 5.71 |
| 414.50 | 5.17 | 5.17 |
| 440.54 | 5.71 | 5.71 |
| 418.46 | 5.00 | 5.00 |
| 444.50 | 5.54 | 5.54 |
| 430.50 | 4.87 | 4.87 |
| 456.54 | 5.37 | 5.37 |
| 434.92 | 5.52 | 5.52 |
| 460.95 | 6.05 | 6.05 |
| 414.50 | 5.17 | 5.17 |
| 440.54 | 5.71 | 5.71 |
| 430.50 | 4.87 | 4.87 |
| 456.54 | 5.41 | 5.41 |
| 388.42 | 3.85 | 3.85 |
| 388.42 | 3.85 | 3.85 |
| 372.42 | 4.15 | 4.15 |
| 376.38 | 3.98 | 3.98 |
| 372.42 | 4.15 | 4.15 |
| 402.44 | 4.24 | 4.24 |
| 402.44 | 4.24 | 4.24 |
| 386.44 | 4.54 | 4.54 |
| 390.41 | 4.37 | 4.37 |
| 386.44 | 4.54 | 4.54 |
| 416.47 | 4.48 | 4.48 |
| 416.47 | 4.48 | 4.48 |
| 400.47 | 4.78 | 4.78 |
| 404.43 | 4.61 | 4.61 |
| 400.47 | 4.78 | 4.78 |
| 416.47 | 4.63 | 4.63 |
| 416.47 | 4.63 | 4.63 |
| 400.47 | 4.93 | 4.93 |
| 404.43 | 4.76 | 4.76 |
| 400.47 | 4.93 | 4.93 |
| 444.52 | 5.26 | 5.26 |
| 444.52 | 5.26 | 5.26 |
| 428.53 | 5.56 | 5.56 |
| 432.49 | 5.39 | 5.39 |