Assay Report Card

Basic Information

ID: ALA3293525

Type: Binding

Description: Ago-Positive allosteric modulator activity at rat mGlu2 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate

Organism: Rattus norvegicus

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
400.474.874.87
426.515.405.40
460.956.056.05
430.504.874.87
416.474.634.63
444.525.265.26
444.525.265.26