Assay Report Card

Basic Information

ID: ALA3293533

Type: Binding

Description: Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/oligo(dT)18 DNA-template primer at 100 uM after 60 mins

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
396.576.116.11
444.573.413.41
428.574.294.29
446.583.393.39
412.575.085.08
428.574.194.19