Basic Information
ID: ALA3294686
Type: Binding
Description: Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3294686
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.61 | 4.82 | 4.82 |
| 442.61 | 3.43 | 3.43 |
| 477.05 | 4.08 | 4.08 |
| 477.05 | 4.08 | 4.08 |
| 460.60 | 3.57 | 3.57 |
| 456.63 | 3.74 | 3.74 |
| 413.57 | 4.13 | 4.13 |
| 448.01 | 4.79 | 4.79 |
| 448.01 | 4.79 | 4.79 |
| 431.56 | 4.27 | 4.27 |
| 427.59 | 4.44 | 4.44 |
| 429.61 | 4.56 | 4.56 |
| 464.05 | 5.22 | 5.22 |
| 464.05 | 5.22 | 5.22 |
| 447.60 | 4.70 | 4.70 |
| 443.64 | 4.87 | 4.87 |
| 427.59 | 4.47 | 4.47 |
| 462.04 | 5.13 | 5.13 |
| 462.04 | 5.13 | 5.13 |
| 445.58 | 4.61 | 4.61 |
| 441.62 | 4.78 | 4.78 |
| 439.60 | 4.62 | 4.62 |
| 474.05 | 5.27 | 5.27 |
| 474.05 | 5.27 | 5.27 |
| 457.59 | 4.76 | 4.76 |
| 453.63 | 4.93 | 4.93 |
| 441.62 | 4.56 | 4.56 |
| 476.06 | 5.22 | 5.22 |
| 476.06 | 5.22 | 5.22 |
| 459.61 | 4.70 | 4.70 |
| 455.65 | 4.87 | 4.87 |