Assay Report Card

Basic Information

ID: ALA3295126

Type: Binding

Description: Inhibition of mPGES1-mediated PGE2 production in microsomes of IL-1beta stimulated human A549 cells assessed as residual activity preincubated at 10 uM for 15 mins by RP-HPLC analysis relative to control

Organism: Homo sapiens

Cell type: A549

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
364.404.184.18
504.626.396.39
338.363.683.68
362.333.693.69
342.352.972.97
508.666.556.55
500.647.207.20