Basic Information
ID: ALA3295135
Type: Binding
Description: Inhibition of purified human COX-2 assessed as residual activity by measuring formation of 12-HHT from arachidonic acid preincubated at 10 uM for 5 mins before substrate addition measured after 5 mins by HPLC analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3295135
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 372.42 | 3.21 | 3.21 |
| 368.39 | 3.85 | 3.85 |
| 326.35 | 3.41 | 3.41 |
| 364.40 | 4.18 | 4.18 |
| 512.69 | 6.39 | 6.39 |
| 504.62 | 6.39 | 6.39 |
| 462.59 | 6.43 | 6.43 |
| 338.36 | 3.68 | 3.68 |
| 404.37 | 3.65 | 3.65 |
| 362.33 | 3.69 | 3.69 |
| 342.35 | 2.97 | 2.97 |
| 508.66 | 6.55 | 6.55 |
| 500.64 | 7.20 | 7.20 |