Basic Information
ID: ALA3295172
Type: Binding
Description: Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA3295172
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.09 | 8.01 | 8.01 |
| 456.71 | 7.09 | 7.09 |
| 470.69 | 6.27 | 6.27 |
| 498.75 | 7.66 | 7.66 |
| 512.73 | 6.84 | 6.84 |
| 454.70 | 7.75 | 7.75 |
| 456.71 | 7.54 | 7.54 |
| 498.75 | 8.11 | 8.11 |
| 456.71 | 7.54 | 7.54 |
| 456.71 | 7.40 | 7.40 |
| 498.75 | 7.97 | 7.97 |
| 440.71 | 8.28 | 8.28 |
| 442.73 | 8.36 | 8.36 |
| 456.71 | 7.54 | 7.54 |
| 442.73 | 8.51 | 8.51 |
| 456.71 | 7.09 | 7.09 |
| 498.75 | 7.66 | 7.66 |
| 514.75 | 6.63 | 6.63 |