Basic Information
ID: ALA3295794
Type: Binding
Description: Antagonist activity at adenosine A2A receptor in 5-HT-treated Wistar rat femoral vein assessed as inhibition of 2-octyn-1-yladenosine-induced vasodilation incubated for 10 mins prior to addition of 5-HT
Organism: Rattus norvegicus
Strain: Wistar
Activity Charts
Bioactivity
Activity Types for Assay ALA3295794
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.44 | 2.12 | 2.12 |
| 257.34 | 2.27 | 2.27 |
| 271.37 | 2.75 | 2.75 |
| 285.39 | 3.14 | 3.14 |
| 283.38 | 2.92 | 2.92 |
| 281.36 | 2.36 | 2.36 |
| 282.35 | 2.25 | 2.25 |
| 287.37 | 1.72 | 1.72 |
| 311.43 | 3.85 | 3.85 |
| 333.44 | 3.78 | 3.78 |
| 360.26 | 3.13 | 3.13 |
| 315.81 | 3.02 | 3.02 |
| 357.46 | 4.03 | 4.03 |
| 375.45 | 4.17 | 4.17 |
| 347.42 | 3.62 | 3.62 |
| 348.41 | 1.94 | 1.94 |
| 295.35 | 1.09 | 1.09 |
| 374.24 | 1.85 | 1.85 |
| 329.79 | 1.74 | 1.74 |
| 361.41 | 2.35 | 2.35 |