Basic Information
ID: ALA3295851
Type: Functional
Description: Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling by fluorescence plate reader analysis in presence of glutamate at EC76 concentration
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3295851
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.49 | 3.17 | 3.17 |
| 351.41 | 4.52 | 4.52 |
| 352.40 | 3.92 | 3.92 |
| 448.48 | 3.31 | 3.31 |
| 370.39 | 4.05 | 4.05 |
| 460.52 | 3.18 | 3.18 |
| 381.44 | 4.53 | 4.53 |
| 382.42 | 3.92 | 3.92 |
| 319.36 | 3.17 | 3.17 |
| 366.42 | 4.22 | 4.22 |
| 386.84 | 4.57 | 4.57 |
| 431.29 | 4.68 | 4.68 |
| 448.48 | 3.31 | 3.31 |
| 399.43 | 4.67 | 4.67 |
| 370.39 | 4.05 | 4.05 |
| 307.33 | 3.30 | 3.30 |
| 464.93 | 3.82 | 3.82 |
| 386.84 | 4.57 | 4.57 |
| 380.41 | 4.04 | 4.04 |
| 382.42 | 3.37 | 3.37 |
| 352.40 | 3.92 | 3.92 |
| 353.39 | 3.31 | 3.31 |
| 391.43 | 4.40 | 4.40 |
| 402.46 | 5.07 | 5.07 |