Basic Information
ID: ALA3296346
Type: Binding
Description: Inhibition of N-terminal His6-tagged recombinant Plasmodium falciparum DHODH (amino acid residues 158 to 569) expressed in Escherichia coli BL21 cells assessed as orotic acid production using dihydroorotate as substrate by DCIP dye-based assay
Organism: Plasmodium falciparum
Cell type: BL21
Activity Charts
Bioactivity
Activity Types for Assay ALA3296346
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.21 | 3.00 | 3.00 |
| 293.25 | 3.20 | 3.20 |
| 357.29 | 4.31 | 4.31 |
| 361.25 | 4.21 | 4.21 |
| 375.28 | 4.45 | 4.45 |
| 393.27 | 4.59 | 4.59 |
| 397.23 | 4.49 | 4.49 |