Basic Information
ID: ALA3296349
Type: Binding
Description: Inhibition of dog DHODH (amino acid residues 48 to 414) expressed in Escherichia coli BL21 cells assessed as orotic acid production using dihydroorotate as substrate by DCIP dye-based assay
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: BL21
Target: Unchecked(ALA612545)
Document: ALA3286300
Inhibition of dog DHODH (amino acid residues 48 to 414) expressed in Escherichia coli BL21 cells assessed as orotic acid production using dihydroorotate as substrate by DCIP dye-based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3296349
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.21 | 3.00 | 3.00 |
| 293.25 | 3.20 | 3.20 |
| 357.29 | 4.31 | 4.31 |
| 329.23 | 3.47 | 3.47 |
| 361.25 | 4.21 | 4.21 |
| 375.28 | 4.45 | 4.45 |
| 393.27 | 4.59 | 4.59 |
| 397.23 | 4.49 | 4.49 |