Basic Information
ID: ALA3296355
Type: Binding
Description: Inhibition of C-terminal His6-tagged human DHODH (amino acid residues 30 to 396) H56A mutant expressed in Escherichia coli BL21 cells assessed as orotic acid production using dihydroorotate as substrate by direct assay in presence of oxygen depleting system
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BL21
Target: Unchecked(ALA612545)
Document: ALA3286300
Inhibition of C-terminal His6-tagged human DHODH (amino acid residues 30 to 396) H56A mutant expressed in Escherichia coli BL21 cells assessed as orotic acid production using dihydroorotate as substrate by direct assay in presence of oxygen depleting system: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3296355
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.21 | 3.00 | 3.00 |
| 357.29 | 4.31 | 4.31 |
| 375.28 | 4.45 | 4.45 |
| 393.27 | 4.59 | 4.59 |
| 397.23 | 4.49 | 4.49 |