Basic Information
ID: ALA3299207
Type: Binding
Description: Inhibition of JAK1/TYK2 in human whole blood assessed as inhibition of IFN-alpha-induced STAT-3 phosphorylation preincubated for 45 mins followed by IFN-alpha addition measured after 15 mins by FACS analysis
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA3299207
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 306.37 | 3.47 | 3.47 |
| 371.43 | 1.10 | 1.10 |
| 392.39 | 3.28 | 3.28 |
| 425.51 | 1.98 | 1.98 |