Basic Information
ID: ALA3299551
Type: Binding
Description: Antagonist activity at human TRPA1 expressed in CHO-TREX cells assessed as inhibition of cinnamaldehyde-induced calcium flux incubated 10 mins prior to cinnamaldehyde addition by FLIPR assay relative to control
Organism: Homo sapiens
Cell type: CHO-TREX
Activity Charts
Bioactivity
Activity Types for Assay ALA3299551
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 228.68 | 3.88 | 3.88 |
| 194.24 | 3.23 | 3.23 |
| 212.23 | 3.37 | 3.37 |
| 208.26 | 3.54 | 3.54 |
| 222.29 | 3.79 | 3.79 |
| 236.32 | 4.35 | 4.35 |
| 250.34 | 4.53 | 4.53 |
| 262.23 | 4.25 | 4.25 |
| 244.24 | 4.17 | 4.17 |
| 278.23 | 4.13 | 4.13 |
| 219.25 | 3.10 | 3.10 |
| 280.22 | 4.39 | 4.39 |
| 280.22 | 4.39 | 4.39 |
| 280.22 | 4.39 | 4.39 |
| 280.22 | 4.39 | 4.39 |
| 280.22 | 4.39 | 4.39 |
| 280.22 | 4.39 | 4.39 |
| 276.26 | 4.56 | 4.56 |
| 276.26 | 4.56 | 4.56 |
| 276.26 | 4.26 | 4.26 |
| 296.68 | 4.90 | 4.90 |
| 276.26 | 4.56 | 4.56 |
| 290.29 | 4.81 | 4.81 |
| 304.32 | 5.37 | 5.37 |
| 302.30 | 5.13 | 5.13 |
| 312.24 | 5.19 | 5.19 |
| 292.26 | 4.26 | 4.26 |
| 306.29 | 4.65 | 4.65 |
| 320.31 | 5.04 | 5.04 |
| 332.33 | 5.04 | 5.04 |
| 306.29 | 4.40 | 4.40 |
| 346.23 | 5.15 | 5.15 |
| 328.24 | 4.85 | 4.85 |
| 287.24 | 4.12 | 4.12 |
| 319.29 | 3.61 | 3.61 |