Assay Report Card

Basic Information

ID: ALA3300764

Type: Functional

Description: In vivo inhibition of BACE-1 in triple transgenic mouse model of Alzheimer's disease assessed as reduction in brain soluble amyloid beta-40 level administered intranasally qd for 4 days by ELISA

Organism: Mus musculus

Tissue: Brain

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
150.222.492.49