ID: ALA3301366
Type: ADME
Description: ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole rat plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound.
Organism: Rattus norvegicus
Strain: SD, HW or BN
Tissue: Plasma
Bioactivity
Activity Types for Assay ALA3301366
PPB
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
383.41 | 1.78 | 1.78 |
331.35 | 1.58 | 1.58 |
280.42 | 3.88 | 3.88 |
284.75 | 3.15 | 3.15 |
252.27 | 1.77 | 1.77 |
454.61 | 5.09 | 5.09 |
398.40 | 3.70 | 3.70 |
407.51 | 4.95 | 4.95 |
307.43 | 2.39 | 2.39 |
401.44 | 2.37 | 2.37 |
330.75 | 1.89 | 1.89 |
248.72 | 2.52 | 2.52 |
309.33 | 4.44 | 4.44 |
326.83 | 3.72 | 3.72 |
263.38 | 3.83 | 3.83 |
267.31 | 1.67 | 1.67 |
359.71 | 4.53 | 4.53 |
250.34 | 3.57 | 3.57 |
385.51 | 2.09 | 2.09 |
395.43 | 2.42 | 2.42 |
375.87 | 4.43 | 4.43 |
347.24 | 2.92 | 2.92 |
287.79 | 3.67 | 3.67 |
275.35 | 2.62 | 2.62 |
494.01 | 3.64 | 3.64 |
370.59 | 5.89 | 5.89 |
285.34 | 1.20 | 1.20 |
318.87 | 4.89 | 4.89 |
266.39 | 3.53 | 3.53 |
329.37 | 3.33 | 3.33 |
382.46 | 5.49 | 5.49 |
473.59 | 6.08 | 6.08 |
410.49 | 3.59 | 3.59 |
261.09 | 1.88 | 1.88 |
248.33 | 1.91 | 1.91 |
379.50 | 4.36 | 4.36 |
259.35 | 2.58 | 2.58 |
528.68 | 1.77 | 1.77 |
354.46 | 3.20 | 3.20 |
324.40 | 3.81 | 3.81 |
409.42 | 4.79 | 4.79 |
236.27 | 3.39 | 3.39 |
179.26 | 2.03 | 2.03 |
194.19 | -1.03 | -1.03 |
403.98 | 3.94 | 3.94 |
254.29 | 3.11 | 3.11 |
123.11 | 0.78 | 0.78 |
670.86 | 3.09 | 3.09 |
613.80 | 2.87 | 2.87 |
341.37 | 5.32 | 5.32 |
241.68 | 0.82 | 0.82 |
194.19 | -0.18 | -0.18 |
337.35 | 1.12 | 1.12 |
371.87 | 2.36 | 2.36 |
188.23 | 1.48 | 1.48 |
341.45 | 3.24 | 3.24 |
336.43 | 2.37 | 2.37 |
284.43 | 4.24 | 4.24 |
325.45 | 2.37 | 2.37 |
414.35 | 3.44 | 3.44 |
325.77 | 4.32 | 4.32 |
277.41 | 4.21 | 4.21 |
272.42 | 3.79 | 3.79 |
275.40 | 4.55 | 4.55 |
343.69 | 3.25 | 3.25 |
296.15 | 4.36 | 4.36 |
412.95 | 3.81 | 3.81 |
239.31 | 1.31 | 1.31 |
312.44 | 3.44 | 3.44 |
406.48 | 3.74 | 3.74 |
437.53 | 4.31 | 4.31 |
452.82 | 2.35 | 2.35 |
256.10 | 2.01 | 2.01 |
237.73 | 2.90 | 2.90 |
422.57 | 3.83 | 3.83 |
270.35 | 1.78 | 1.78 |
306.24 | 5.18 | 5.18 |
896.11 | 1.32 | 1.32 |
404.49 | 3.80 | 3.80 |
392.41 | 2.35 | 2.35 |
435.44 | -1.17 | -1.17 |
303.34 | 3.59 | 3.59 |
477.05 | 5.09 | 5.09 |
371.28 | 2.68 | 2.68 |
336.44 | 2.75 | 2.75 |
262.32 | 3.22 | 3.22 |
250.20 | 3.04 | 3.04 |
436.90 | 4.47 | 4.47 |
501.67 | 5.51 | 5.51 |
401.54 | 2.31 | 2.31 |
221.65 | 2.08 | 2.08 |
720.96 | 5.91 | 5.91 |
493.62 | 4.59 | 4.59 |
229.63 | -1.08 | -1.08 |
481.34 | 4.76 | 4.76 |
216.28 | 1.77 | 1.77 |
551.63 | 4.20 | 4.20 |
393.47 | 4.32 | 4.32 |
448.38 | 5.88 | 5.88 |
452.47 | 4.01 | 4.01 |
345.73 | 2.00 | 2.00 |
514.63 | 7.26 | 7.26 |
257.29 | 2.19 | 2.19 |
373.47 | 3.83 | 3.83 |
375.56 | 5.04 | 5.04 |
464.61 | 2.90 | 2.90 |
351.41 | 3.85 | 3.85 |
159.23 | 1.08 | 1.08 |
293.32 | 4.03 | 4.03 |
364.42 | 3.04 | 3.04 |
445.55 | 2.08 | 2.08 |
256.33 | 3.71 | 3.71 |
328.38 | 3.89 | 3.89 |
322.41 | 3.74 | 3.74 |
448.39 | 4.86 | 4.86 |
313.79 | 3.43 | 3.43 |
380.41 | 4.18 | 4.18 |
168.20 | 2.02 | 2.02 |
154.12 | 0.80 | 0.80 |
313.42 | 1.13 | 1.13 |
391.47 | 4.88 | 4.88 |
399.88 | 2.61 | 2.61 |
873.03 | 1.03 | 1.03 |
327.42 | 2.80 | 2.80 |
368.48 | 3.84 | 3.84 |
424.53 | 2.44 | 2.44 |
482.67 | 5.38 | 5.38 |
430.57 | 3.85 | 3.85 |
443.57 | 2.95 | 2.95 |
442.63 | 5.44 | 5.44 |
588.56 | 1.34 | 1.34 |
610.58 | 2.32 | 2.32 |
521.44 | 4.87 | 4.87 |
310.83 | 4.02 | 4.02 |
499.53 | -0.16 | -0.16 |
589.18 | 4.56 | 4.56 |
277.76 | 2.21 | 2.21 |
373.35 | 2.77 | 2.77 |
402.39 | 2.76 | 2.76 |
415.57 | 4.11 | 4.11 |
380.40 | 2.38 | 2.38 |
240.31 | 2.82 | 2.82 |
473.41 | 7.49 | 7.49 |
324.42 | 3.17 | 3.17 |
242.27 | 3.67 | 3.67 |
450.54 | 5.26 | 5.26 |
295.37 | 4.45 | 4.45 |
280.32 | 4.25 | 4.25 |
366.36 | 1.72 | 1.72 |
382.36 | 0.96 | 0.96 |
164.23 | 2.06 | 2.06 |
426.56 | 3.96 | 3.96 |
496.53 | 2.12 | 2.12 |
416.47 | 3.09 | 3.09 |
469.89 | 3.38 | 3.38 |
381.90 | 1.81 | 1.81 |
344.41 | 2.22 | 2.22 |
403.21 | 5.03 | 5.03 |
296.42 | 4.17 | 4.17 |
483.57 | 3.58 | 3.58 |
435.89 | 2.52 | 2.52 |
380.42 | 2.09 | 2.09 |
314.39 | 2.47 | 2.47 |
427.55 | 2.31 | 2.31 |
589.64 | 4.59 | 4.59 |
347.41 | 5.11 | 5.11 |
464.52 | 4.46 | 4.46 |
318.34 | 2.61 | 2.61 |
315.33 | 0.78 | 0.78 |
237.26 | 2.82 | 2.82 |
485.63 | 4.17 | 4.17 |
360.44 | 3.82 | 3.82 |
307.40 | 2.64 | 2.64 |
451.92 | 0.09 | 0.09 |
422.32 | 2.22 | 2.22 |
422.32 | 2.22 | 2.22 |
364.83 | 5.21 | 5.21 |
482.01 | 5.25 | 5.25 |
407.32 | 2.02 | 2.02 |
461.56 | 5.86 | 5.86 |
425.92 | 3.35 | 3.35 |
397.43 | 2.90 | 2.90 |
418.45 | 2.97 | 2.97 |
392.47 | 1.90 | 1.90 |
225.21 | -1.33 | -1.33 |
367.83 | 4.76 | 4.76 |
339.47 | 4.10 | 4.10 |
362.23 | 4.06 | 4.06 |
420.47 | 2.03 | 2.03 |
388.40 | 3.76 | 3.76 |
376.40 | 3.97 | 3.97 |
491.60 | 6.03 | 6.03 |
166.25 | 1.28 | 1.28 |
299.37 | 2.80 | 2.80 |
316.32 | 3.33 | 3.33 |
180.17 | -1.04 | -1.04 |
389.82 | 3.68 | 3.68 |
430.41 | 5.52 | 5.52 |
586.61 | 6.53 | 6.53 |
603.60 | 5.81 | 5.81 |
311.34 | 3.03 | 3.03 |
563.65 | 5.56 | 5.56 |
308.33 | 3.61 | 3.61 |
534.43 | 4.95 | 4.95 |
401.98 | 3.69 | 3.69 |
500.58 | 4.43 | 4.43 |
489.60 | 2.93 | 2.93 |
459.56 | 4.88 | 4.88 |
328.39 | 3.12 | 3.12 |
265.34 | 3.24 | 3.24 |
479.53 | 3.68 | 3.68 |
474.59 | 1.61 | 1.61 |
408.35 | 5.00 | 5.00 |
439.56 | 5.04 | 5.04 |
549.59 | 4.89 | 4.89 |
304.32 | 2.98 | 2.98 |
360.45 | 1.99 | 1.99 |
346.34 | 2.18 | 2.18 |
384.26 | 3.96 | 3.96 |
114.17 | 0.71 | 0.71 |
170.24 | 1.38 | 1.38 |
553.59 | 5.25 | 5.25 |
453.42 | 4.13 | 4.13 |
428.49 | 3.09 | 3.09 |
268.65 | 3.27 | 3.27 |
437.50 | 0.90 | 0.90 |
465.35 | 4.94 | 4.94 |
308.32 | 2.38 | 2.38 |
490.82 | 4.53 | 4.53 |
492.66 | 3.77 | 3.77 |
361.44 | 0.38 | 0.38 |
505.53 | 3.56 | 3.56 |
343.42 | 4.05 | 4.05 |
463.89 | 4.53 | 4.53 |
360.37 | 2.57 | 2.57 |
259.35 | 2.58 | 2.58 |
351.45 | 3.19 | 3.19 |
427.89 | 4.93 | 4.93 |
389.34 | 4.82 | 4.82 |
295.39 | 1.75 | 1.75 |
445.51 | 2.95 | 2.95 |
437.52 | 3.68 | 3.68 |
437.52 | 3.68 | 3.68 |
525.57 | 4.63 | 4.63 |
457.94 | 4.02 | 4.02 |
311.86 | 2.48 | 2.48 |
395.46 | 3.77 | 3.77 |
400.22 | 3.17 | 3.17 |
474.30 | 2.35 | 2.35 |
453.61 | 4.25 | 4.25 |
408.45 | 3.02 | 3.02 |
263.34 | 4.05 | 4.05 |
404.56 | 3.94 | 3.94 |
448.49 | 2.57 | 2.57 |
543.05 | 2.65 | 2.65 |
427.46 | -0.54 | -0.54 |
349.48 | 3.58 | 3.58 |
645.68 | -1.11 | -1.11 |
176.18 | 0.08 | 0.08 |
479.94 | 3.46 | 3.46 |
357.37 | 3.67 | 3.67 |
373.82 | 4.18 | 4.18 |
481.92 | 2.82 | 2.82 |
264.33 | 3.66 | 3.66 |
274.32 | 3.79 | 3.79 |
406.45 | 3.07 | 3.07 |
391.74 | 2.78 | 2.78 |
277.41 | 2.61 | 2.61 |
463.55 | 3.83 | 3.83 |
569.58 | 5.19 | 5.19 |
392.46 | 5.28 | 5.28 |
262.70 | 3.00 | 3.00 |
405.24 | 2.20 | 2.20 |
423.94 | 5.65 | 5.65 |
378.44 | 5.27 | 5.27 |
348.38 | 4.31 | 4.31 |
212.21 | 1.30 | 1.30 |
392.84 | 1.39 | 1.39 |
424.81 | 3.85 | 3.85 |
501.51 | 4.10 | 4.10 |
474.50 | 5.10 | 5.10 |
438.83 | 4.41 | 4.41 |
568.59 | 6.68 | 6.68 |
367.49 | 3.83 | 3.83 |
449.40 | 2.85 | 2.85 |
401.89 | 4.52 | 4.52 |
414.89 | 2.52 | 2.52 |
410.51 | 3.07 | 3.07 |
232.67 | 2.99 | 2.99 |
419.57 | 4.30 | 4.30 |
419.50 | 2.19 | 2.19 |
419.50 | 2.19 | 2.19 |
518.60 | 3.93 | 3.93 |
430.82 | 5.86 | 5.86 |
581.47 | 5.75 | 5.75 |
364.39 | 3.40 | 3.40 |
339.34 | 2.23 | 2.23 |
353.37 | 2.53 | 2.53 |
352.38 | 3.14 | 3.14 |
338.35 | 2.83 | 2.83 |
504.01 | 2.38 | 2.38 |
422.44 | 3.37 | 3.37 |
294.81 | 4.17 | 4.17 |
416.81 | 4.75 | 4.75 |
450.35 | 5.04 | 5.04 |
326.78 | 4.58 | 4.58 |
386.45 | 2.38 | 2.38 |
460.62 | 6.14 | 6.14 |
360.41 | 3.05 | 3.05 |
274.41 | 3.51 | 3.51 |
311.41 | 2.18 | 2.18 |
311.41 | 2.18 | 2.18 |
520.89 | 3.92 | 3.92 |
477.31 | 4.43 | 4.43 |
383.47 | 3.86 | 3.86 |
349.48 | 3.58 | 3.58 |
371.40 | 1.56 | 1.56 |
475.54 | 3.87 | 3.87 |
470.60 | 4.78 | 4.78 |
777.89 | 1.92 | 1.92 |
355.40 | 1.20 | 1.20 |
491.75 | 5.41 | 5.41 |
316.38 | 3.72 | 3.72 |
318.44 | 2.46 | 2.46 |
436.59 | 4.11 | 4.11 |
421.47 | 4.52 | 4.52 |
415.86 | 3.22 | 3.22 |
491.61 | 5.39 | 5.39 |
397.44 | 2.77 | 2.77 |
507.53 | 4.28 | 4.28 |
400.50 | 3.06 | 3.06 |
374.47 | 4.36 | 4.36 |
423.90 | 3.66 | 3.66 |
617.77 | 4.64 | 4.64 |
502.64 | 1.96 | 1.96 |
501.03 | 5.42 | 5.42 |
196.16 | -0.40 | -0.40 |
518.49 | -1.41 | -1.41 |
439.38 | 5.76 | 5.76 |
421.81 | 4.67 | 4.67 |
459.59 | 2.88 | 2.88 |
339.40 | 4.23 | 4.23 |
524.69 | 4.82 | 4.82 |
352.46 | 3.23 | 3.23 |
414.51 | 3.86 | 3.86 |
382.94 | 4.86 | 4.86 |
362.52 | 4.51 | 4.51 |
297.34 | 2.46 | 2.46 |
312.76 | 3.82 | 3.82 |
359.86 | 3.24 | 3.24 |
290.39 | 2.49 | 2.49 |
266.38 | 1.31 | 1.31 |
311.37 | 3.55 | 3.55 |
255.36 | 3.95 | 3.95 |
281.38 | 1.29 | 1.29 |
331.79 | 3.90 | 3.90 |
430.90 | 5.90 | 5.90 |
309.76 | 4.11 | 4.11 |
249.32 | 3.43 | 3.43 |
392.50 | 4.09 | 4.09 |
489.60 | 4.30 | 4.30 |
418.50 | 1.14 | 1.14 |
355.18 | 3.14 | 3.14 |
454.57 | 2.18 | 2.18 |
340.46 | 4.37 | 4.37 |
394.54 | 4.26 | 4.26 |
253.26 | 2.81 | 2.81 |
342.68 | 4.14 | 4.14 |
325.32 | 2.06 | 2.06 |
318.42 | 3.71 | 3.71 |
332.45 | 4.02 | 4.02 |
332.45 | 3.74 | 3.74 |
362.43 | 3.18 | 3.18 |
260.72 | 2.71 | 2.71 |
315.76 | 4.28 | 4.28 |
415.86 | 3.02 | 3.02 |
502.66 | 5.42 | 5.42 |
318.34 | 3.20 | 3.20 |
416.36 | 1.89 | 1.89 |
320.48 | 3.60 | 3.60 |
279.38 | 3.96 | 3.96 |
442.32 | 3.77 | 3.77 |
485.37 | 5.46 | 5.46 |
349.76 | 2.97 | 2.97 |
355.50 | 1.68 | 1.68 |
525.61 | 4.23 | 4.23 |
479.58 | 4.59 | 4.59 |
438.51 | 3.07 | 3.07 |
428.44 | 2.51 | 2.51 |
424.48 | 2.68 | 2.68 |
378.39 | 4.32 | 4.32 |
424.91 | 2.31 | 2.31 |
438.93 | 2.45 | 2.45 |
442.90 | 2.45 | 2.45 |
416.91 | 3.08 | 3.08 |
434.90 | 3.22 | 3.22 |
451.35 | 3.73 | 3.73 |
302.36 | 3.25 | 3.25 |
309.37 | 2.52 | 2.52 |
482.63 | 4.77 | 4.77 |
254.29 | 2.15 | 2.15 |
333.40 | 4.70 | 4.70 |
571.78 | 4.23 | 4.23 |
386.45 | 3.67 | 3.67 |
423.54 | 5.24 | 5.24 |
394.50 | 4.49 | 4.49 |
440.57 | 5.18 | 5.18 |
380.40 | 4.75 | 4.75 |
431.43 | 3.87 | 3.87 |
321.25 | 3.71 | 3.71 |
287.70 | 3.34 | 3.34 |
408.78 | 3.89 | 3.89 |
422.81 | 4.28 | 4.28 |
402.39 | 3.94 | 3.94 |
375.23 | 3.53 | 3.53 |
372.80 | 3.40 | 3.40 |
370.80 | 1.55 | 1.55 |
480.95 | 0.87 | 0.87 |
349.43 | 3.09 | 3.09 |
306.37 | 3.47 | 3.47 |
429.66 | 6.50 | 6.50 |
474.27 | 5.15 | 5.15 |
485.65 | 3.71 | 3.71 |
637.51 | 9.76 | 9.76 |
367.36 | 3.26 | 3.26 |
498.67 | 4.45 | 4.45 |
432.54 | 2.58 | 2.58 |
447.63 | 2.87 | 2.87 |
516.52 | 4.18 | 4.18 |
516.52 | 4.97 | 4.97 |
473.62 | 5.96 | 5.96 |
423.56 | 4.81 | 4.81 |
474.61 | 5.36 | 5.36 |
502.66 | 5.42 | 5.42 |
534.71 | 4.72 | 4.72 |
552.76 | 3.98 | 3.98 |
524.71 | 4.89 | 4.89 |
551.78 | 5.46 | 5.46 |
523.72 | 4.86 | 4.86 |
539.72 | 4.06 | 4.06 |
579.79 | 4.58 | 4.58 |
579.79 | 4.84 | 4.84 |
565.80 | 5.71 | 5.71 |
551.78 | 5.46 | 5.46 |
480.95 | 0.87 | 0.87 |
337.38 | 2.66 | 2.66 |
434.97 | 2.65 | 2.65 |
293.17 | 3.18 | 3.18 |
284.34 | 3.56 | 3.56 |
360.17 | 2.32 | 2.32 |
392.52 | 2.35 | 2.35 |
420.45 | 2.08 | 2.08 |
426.54 | 3.90 | 3.90 |
452.58 | 4.39 | 4.39 |
446.53 | 3.91 | 3.91 |
404.54 | 3.48 | 3.48 |
426.54 | 3.90 | 3.90 |
427.53 | 3.29 | 3.29 |
519.63 | 5.12 | 5.12 |
440.57 | 4.21 | 4.21 |
412.52 | 3.43 | 3.43 |
452.58 | 4.35 | 4.35 |
466.61 | 4.60 | 4.60 |
454.55 | 3.20 | 3.20 |
440.57 | 4.07 | 4.07 |
426.54 | 3.82 | 3.82 |
454.60 | 4.45 | 4.45 |
454.60 | 4.45 | 4.45 |
454.60 | 4.45 | 4.45 |
508.57 | 5.16 | 5.16 |
539.70 | 3.98 | 3.98 |
446.62 | 4.42 | 4.42 |
483.57 | 4.16 | 4.16 |
526.56 | 5.30 | 5.30 |
424.93 | 4.21 | 4.21 |
409.90 | 5.30 | 5.30 |
476.64 | 4.18 | 4.18 |
421.51 | 4.12 | 4.12 |
381.49 | 3.41 | 3.41 |
305.44 | 2.25 | 2.25 |
447.64 | 4.78 | 4.78 |
391.32 | 4.34 | 4.34 |
406.55 | 3.80 | 3.80 |
420.58 | 4.05 | 4.05 |
406.55 | 3.49 | 3.49 |
460.52 | 4.03 | 4.03 |
448.63 | 4.83 | 4.83 |
432.59 | 4.19 | 4.19 |
446.62 | 4.58 | 4.58 |
460.64 | 4.97 | 4.97 |
450.61 | 3.67 | 3.67 |
464.63 | 4.06 | 4.06 |
478.68 | 4.53 | 4.53 |
510.68 | 3.21 | 3.21 |
462.62 | 3.82 | 3.82 |
488.65 | 4.39 | 4.39 |
381.86 | 4.26 | 4.26 |
472.98 | 5.25 | 5.25 |
700.29 | 7.80 | 7.80 |
651.08 | 5.55 | 5.55 |
481.59 | 3.63 | 3.63 |
493.63 | 3.50 | 3.50 |
493.63 | 3.50 | 3.50 |
464.59 | 2.89 | 2.89 |
464.59 | 2.89 | 2.89 |
479.60 | 3.46 | 3.46 |
417.53 | 1.90 | 1.90 |
457.00 | 5.53 | 5.53 |
372.82 | 4.90 | 4.90 |
360.42 | 2.53 | 2.53 |
344.80 | 2.03 | 2.03 |
542.10 | 3.75 | 3.75 |
316.47 | 3.53 | 3.53 |
538.66 | 2.60 | 2.60 |
330.49 | 3.92 | 3.92 |
364.45 | 3.01 | 3.01 |
468.54 | 3.77 | 3.77 |
458.49 | 3.35 | 3.35 |
471.01 | 3.38 | 3.38 |
485.03 | 3.60 | 3.60 |
492.50 | 3.02 | 3.02 |
506.53 | 3.58 | 3.58 |
466.59 | 3.08 | 3.08 |
484.58 | 3.22 | 3.22 |
473.58 | 2.69 | 2.69 |
384.66 | 2.76 | 2.76 |
415.45 | 4.16 | 4.16 |
409.92 | 4.68 | 4.68 |
505.02 | 4.25 | 4.25 |
549.07 | 4.00 | 4.00 |
654.60 | -2.90 | -2.90 |
450.01 | 2.91 | 2.91 |
756.97 | 6.34 | 6.34 |
423.56 | 3.06 | 3.06 |
425.57 | 3.31 | 3.31 |
237.26 | 2.38 | 2.38 |
511.69 | 3.98 | 3.98 |
538.65 | 3.53 | 3.53 |
276.29 | 1.29 | 1.29 |
323.81 | 2.20 | 2.20 |
500.59 | 1.61 | 1.61 |
516.58 | 0.85 | 0.85 |
244.13 | 2.75 | 2.75 |
434.50 | 5.76 | 5.76 |
382.46 | 4.01 | 4.01 |
354.38 | 3.60 | 3.60 |
348.40 | 4.44 | 4.44 |
432.53 | 2.06 | 2.06 |
459.42 | 3.31 | 3.31 |
503.48 | 3.33 | 3.33 |
444.41 | 3.52 | 3.52 |
326.35 | 3.23 | 3.23 |
299.35 | 3.46 | 3.46 |
306.37 | 3.20 | 3.20 |
408.81 | 4.87 | 4.87 |
329.83 | 4.37 | 4.37 |
428.79 | 4.90 | 4.90 |
262.74 | 1.44 | 1.44 |
371.44 | 2.51 | 2.51 |
496.67 | 1.19 | 1.19 |
495.69 | 2.53 | 2.53 |
399.29 | 3.35 | 3.35 |
396.50 | 2.28 | 2.28 |
232.35 | 3.84 | 3.84 |
546.72 | 2.72 | 2.72 |
349.47 | 2.64 | 2.64 |
359.42 | 3.71 | 3.71 |
527.48 | 5.52 | 5.52 |
451.53 | 5.04 | 5.04 |
460.46 | 4.16 | 4.16 |
464.42 | 3.99 | 3.99 |
471.44 | 3.72 | 3.72 |
482.41 | 4.15 | 4.15 |
464.42 | 3.91 | 3.91 |
478.45 | 4.05 | 4.05 |
466.41 | 4.18 | 4.18 |
482.41 | 4.15 | 4.15 |
500.40 | 4.29 | 4.29 |
468.96 | 4.93 | 4.93 |
449.50 | 4.35 | 4.35 |
430.43 | 4.21 | 4.21 |
435.53 | 4.25 | 4.25 |
322.40 | 3.13 | 3.13 |
338.35 | 2.55 | 2.55 |
397.41 | 2.61 | 2.61 |
415.40 | 2.94 | 2.94 |
401.38 | 2.55 | 2.55 |
387.35 | 2.16 | 2.16 |
348.53 | 5.44 | 5.44 |
348.53 | 5.44 | 5.44 |
320.48 | 4.66 | 4.66 |
320.48 | 4.66 | 4.66 |
476.56 | 4.76 | 4.76 |
453.38 | 4.63 | 4.63 |
458.42 | 5.08 | 5.08 |
286.34 | 1.22 | 1.22 |
336.40 | 2.37 | 2.37 |
355.23 | 2.53 | 2.53 |
320.78 | 1.87 | 1.87 |
355.23 | 2.53 | 2.53 |
516.47 | 5.12 | 5.12 |
516.47 | 5.12 | 5.12 |
505.49 | 5.55 | 5.55 |
523.48 | 5.69 | 5.69 |
514.04 | 4.91 | 4.91 |
537.50 | 6.08 | 6.08 |
503.06 | 5.43 | 5.43 |
486.60 | 4.91 | 4.91 |
491.46 | 5.24 | 5.24 |
509.45 | 5.38 | 5.38 |
474.41 | 3.57 | 3.57 |
492.40 | 3.71 | 3.71 |
476.40 | 3.83 | 3.83 |
490.41 | 3.28 | 3.28 |
469.46 | 4.42 | 4.42 |
456.42 | 3.43 | 3.43 |
474.41 | 3.57 | 3.57 |
434.41 | 3.58 | 3.58 |
434.41 | 3.58 | 3.58 |
468.42 | 4.98 | 4.98 |
455.44 | 4.04 | 4.04 |
470.45 | 3.47 | 3.47 |
351.41 | 2.61 | 2.61 |
377.37 | 3.47 | 3.47 |
378.35 | 3.97 | 3.97 |
377.37 | 3.50 | 3.50 |
461.52 | 1.26 | 1.26 |
461.52 | 1.26 | 1.26 |
475.55 | 1.92 | 1.92 |
476.51 | 1.80 | 1.80 |
350.42 | 2.40 | 2.40 |
380.45 | 1.76 | 1.76 |
394.48 | 2.15 | 2.15 |
350.42 | 2.76 | 2.76 |
256.26 | 3.38 | 3.38 |
577.55 | 4.55 | 4.55 |
536.66 | 1.91 | 1.91 |
393.45 | 1.58 | 1.58 |
524.70 | 4.27 | 4.27 |
369.49 | 3.83 | 3.83 |
403.43 | 4.24 | 4.24 |
395.50 | 4.42 | 4.42 |
495.87 | 4.37 | 4.37 |
463.32 | 3.08 | 3.08 |
395.50 | 4.42 | 4.42 |
353.47 | 3.52 | 3.52 |
325.41 | 2.90 | 2.90 |
366.47 | 3.01 | 3.01 |
452.56 | 3.50 | 3.50 |
444.56 | 2.60 | 2.60 |
353.42 | 3.30 | 3.30 |
339.40 | 2.99 | 2.99 |
483.95 | 4.39 | 4.39 |
483.95 | 4.39 | 4.39 |
512.01 | 5.17 | 5.17 |
512.01 | 5.17 | 5.17 |
526.03 | 5.41 | 5.41 |
526.03 | 5.41 | 5.41 |
584.51 | 5.91 | 5.91 |
344.39 | 3.92 | 3.92 |
371.44 | 3.49 | 3.49 |
324.82 | 3.80 | 3.80 |
328.42 | 3.51 | 3.51 |
484.37 | 5.85 | 5.85 |
500.52 | 5.74 | 5.74 |
381.43 | 3.49 | 3.49 |
378.43 | 2.99 | 2.99 |
325.37 | 2.38 | 2.38 |
391.95 | ||
425.50 | ||
522.35 | 3.35 | 3.35 |
428.50 | 4.37 | 4.37 |
440.55 | 4.89 | 4.89 |
580.72 | 2.30 | 2.30 |
326.34 | 3.82 | 3.82 |
360.40 | 4.70 | 4.70 |
413.48 | 4.24 | 4.24 |
350.40 | 4.09 | 4.09 |
336.38 | 4.23 | 4.23 |
385.41 | 4.41 | 4.41 |
352.37 | 3.46 | 3.46 |
435.55 | 3.90 | 3.90 |
495.60 | 3.53 | 3.53 |
465.58 | 3.52 | 3.52 |
436.54 | 3.29 | 3.29 |
539.65 | 3.28 | 3.28 |
464.52 | 2.80 | 2.80 |
390.44 | 3.42 | 3.42 |
473.58 | 3.23 | 3.23 |
378.31 | 3.78 | 3.78 |
531.90 | 5.40 | 5.40 |
500.36 | 5.15 | 5.15 |
504.48 | 4.48 | 4.48 |
533.92 | 5.52 | 5.52 |
538.99 | 4.41 | 4.41 |
547.45 | 4.92 | 4.92 |
545.93 | 5.59 | 5.59 |
487.87 | 4.59 | 4.59 |
524.96 | 4.07 | 4.07 |
469.88 | 4.45 | 4.45 |
576.10 | 3.21 | 3.21 |
576.10 | 3.21 | 3.21 |
427.51 | 4.65 | 4.65 |
383.46 | 4.63 | 4.63 |
387.31 | 2.51 | 2.51 |
415.37 | 3.29 | 3.29 |
445.39 | 2.65 | 2.65 |
459.42 | 2.90 | 2.90 |
389.58 | 2.51 | 2.51 |
390.57 | 1.60 | 1.60 |
419.61 | 1.79 | 1.79 |
439.67 | 2.29 | 2.29 |
454.68 | 1.65 | 1.65 |
429.39 | 3.53 | 3.53 |
431.36 | 2.52 | 2.52 |
415.37 | 3.14 | 3.14 |
415.54 | 3.68 | 3.68 |