Assay Report Card

Basic Information

ID: ALA3301566

Type: Functional

Description: MMV: CDPK1 Protein kinase inhibition assay using recombinant PfCDPK1, syntide 2 peptide substrate, ATP and KinaseGlo to measure % inhibition at 1 uM MMV box compound.

Organism: Plasmodium falciparum

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
350.035.945.94
291.403.883.88
367.493.733.73
243.22-2.56-2.56
277.803.643.64
368.484.884.88
279.393.753.75
288.313.363.36
337.184.124.12
348.412.032.03
245.282.682.68
272.313.663.66
440.465.395.39
325.594.754.75
267.364.264.26
319.454.594.59
275.313.333.33
273.332.442.44
346.403.333.33
270.334.904.90
339.353.313.31
302.762.962.96
361.234.164.16
297.791.271.27
290.253.793.79
441.864.824.82
405.504.804.80
338.284.624.62
359.411.471.47
347.263.783.78
332.364.704.70
298.774.954.95
444.604.994.99
403.444.514.51
278.313.903.90
420.516.716.71
368.664.804.80
323.353.093.09
367.283.703.70
249.752.912.91
442.326.406.40
510.437.687.68
571.687.187.18
383.674.944.94
393.404.514.51
476.057.297.29
448.377.157.15
372.425.135.13
465.593.983.98
431.566.926.92
367.412.532.53
456.985.345.34
412.495.475.47
479.853.903.90
398.515.205.20
497.754.594.59
354.474.024.02
440.533.523.52
413.534.114.11
307.863.703.70
420.685.555.55
359.773.663.66
420.493.683.68
484.963.173.17
500.583.673.67
397.504.244.24
341.445.945.94
574.245.295.29
384.504.034.03
346.434.204.20
346.822.792.79
436.585.225.22
418.594.274.27
261.414.114.11
385.875.305.30
456.514.034.03
377.874.094.09
328.174.124.12
493.614.004.00
381.824.254.25
319.363.473.47
391.494.524.52
343.394.494.49
309.823.803.80
252.322.882.88
636.7110.4510.45
491.544.324.32
413.525.595.59
397.543.753.75
354.414.464.46
189.221.531.53
312.424.344.34
438.904.044.04
326.454.464.46
292.343.423.42
362.444.244.24
281.282.922.92
420.184.454.45
403.924.794.79
307.382.492.49
487.776.436.43
389.803.673.67
507.054.874.87
441.334.794.79
430.525.535.53
400.954.574.57
218.261.351.35
286.773.263.26
462.433.683.68
495.074.074.07
432.363.283.28
459.936.396.39
456.985.345.34
480.015.375.37
349.534.704.70
366.355.455.45
309.323.383.38
422.445.335.33
322.454.084.08
341.724.164.16
726.975.875.87
494.563.013.01
370.493.803.80
303.393.913.91
496.017.337.33
447.546.426.42
434.543.953.95
494.664.964.96
329.382.382.38
340.403.763.76
431.325.345.34
459.624.694.69
340.794.724.72
357.414.884.88
364.455.255.25
493.404.644.64
448.524.304.30
377.874.644.64
515.157.637.63
388.524.854.85
458.635.305.30
373.414.504.50
457.834.304.30
327.703.853.85
479.543.313.31
367.535.105.10
470.176.646.64
422.324.754.75
426.544.884.88
347.844.634.63
445.535.145.14
268.323.003.00
586.755.635.63
465.627.407.40
280.173.963.96
353.381.401.40
393.492.912.91
356.434.994.99
405.503.623.62
387.496.346.34
496.505.205.20
228.343.173.17
434.495.475.47
283.714.014.01
371.872.832.83
199.252.412.41
298.775.035.03
378.494.124.12
453.335.785.78
468.343.783.78
199.252.982.98
423.433.393.39
274.393.853.85
267.343.053.05
453.558.408.40
265.322.982.98
260.350.940.94
460.546.386.38
326.404.994.99
316.794.004.00
332.514.234.23
427.322.762.76
422.963.073.07
384.313.953.95
380.444.794.79
341.424.764.76
319.433.523.52
554.517.907.90
328.202.532.53
268.144.114.11
445.523.513.51
274.323.413.41
362.433.883.88
419.486.336.33
659.696.646.64
293.323.783.78
345.832.902.90
413.596.796.79
337.435.525.52
359.435.615.61
201.273.203.20
334.383.523.52
357.412.072.07
496.695.565.56
645.206.866.86
346.903.793.79
376.434.974.97
347.844.084.08
318.334.394.39
394.433.543.54
382.872.652.65
484.605.965.96
463.964.654.65
287.374.444.44
287.794.314.31
314.434.754.75
546.607.487.48
335.843.433.43
440.293.003.00
338.284.624.62
335.453.893.89
307.444.534.53
232.713.493.49
371.465.955.95
284.753.923.92
292.514.084.08
334.393.583.58
420.566.036.03
460.564.894.89
362.444.504.50
331.422.602.60
480.595.345.34
391.414.144.14
286.333.963.96
358.393.933.93
301.413.913.91
261.753.903.90
355.444.974.97
420.336.706.70
389.365.795.79
354.815.785.78
348.404.674.67
356.435.575.57
469.015.995.99
592.668.208.20
409.514.624.62
360.893.323.32
451.577.357.35
294.453.503.50
349.863.963.96
396.924.964.96
357.894.754.75
282.552.732.73
579.129.649.64
662.873.603.60
287.321.311.31
268.363.673.67
308.364.284.28
289.344.034.03
290.252.922.92
245.282.272.27
320.404.154.15
480.597.287.28
357.255.455.45
335.323.563.56
309.413.343.34
637.735.505.50
420.513.923.92
308.393.393.39
245.323.603.60
279.343.293.29
312.192.552.55
265.402.822.82
382.255.795.79
657.777.707.70
273.723.533.53
410.431.581.58
500.195.135.13
359.483.733.73
349.224.084.08
274.322.762.76
524.587.527.52
362.273.633.63
621.787.237.23
501.377.047.04
426.596.096.09
631.737.207.20
406.515.015.01
286.764.344.34
357.812.132.13
348.195.215.21
469.313.613.61
305.853.633.63
389.544.174.17
380.364.824.82
559.646.406.40
416.524.174.17
312.412.722.72
390.514.424.42
448.595.015.01
291.823.073.07
254.333.283.28
368.915.095.09
286.204.114.11
282.162.542.54
366.893.953.95
434.565.335.33
293.533.633.63
336.394.034.03
462.625.405.40
432.915.435.43
414.494.734.73
377.914.044.04
417.444.964.96
468.475.095.09
411.965.825.82
293.323.763.76
310.424.854.85
303.794.094.09
436.015.105.10
391.904.484.48
411.634.274.27
360.244.224.22
367.414.094.09
314.473.793.79
458.865.495.49
333.585.435.43
327.434.184.18
363.464.654.65
314.824.554.55
453.583.843.84
395.535.205.20
355.953.723.72
425.964.844.84
458.634.564.56
281.144.294.29
278.714.434.43
400.464.424.42
315.844.994.99
352.795.615.61
425.964.844.84
450.585.355.35
350.855.535.53
315.684.324.32
416.294.164.16
321.803.403.40
383.493.793.79
487.033.593.59
417.984.254.25
308.433.693.69
395.734.134.13
297.242.352.35
279.413.293.29
384.503.673.67
398.465.245.24
401.895.655.65
403.953.863.86
472.474.434.43
440.554.764.76
329.843.613.61
309.332.182.18
368.403.793.79
392.422.282.28
468.118.208.20
431.374.604.60
363.894.354.35
254.311.621.62
254.273.093.09
335.833.573.57
393.314.234.23
280.334.004.00
310.383.593.59
358.446.346.34
321.313.813.81
341.330.310.31
490.675.475.47
380.493.693.69
519.985.525.52
487.696.596.59
485.656.656.65
489.525.365.36
420.494.834.83
401.514.704.70
396.485.115.11
492.915.815.81
476.916.116.11
472.455.305.30
317.823.523.52
301.782.522.52
311.394.854.85
491.955.685.68
341.414.864.86
484.606.206.20
405.483.933.93
352.442.432.43
348.314.544.54
465.474.324.32
389.886.116.11
493.575.115.11
313.362.812.81