ID: ALA3301566
Type: Functional
Description: MMV: CDPK1 Protein kinase inhibition assay using recombinant PfCDPK1, syntide 2 peptide substrate, ATP and KinaseGlo to measure % inhibition at 1 uM MMV box compound.
Organism: Plasmodium falciparum
Bioactivity
Activity Types for Assay ALA3301566
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
350.03 | 5.94 | 5.94 |
291.40 | 3.88 | 3.88 |
367.49 | 3.73 | 3.73 |
243.22 | -2.56 | -2.56 |
277.80 | 3.64 | 3.64 |
368.48 | 4.88 | 4.88 |
279.39 | 3.75 | 3.75 |
288.31 | 3.36 | 3.36 |
337.18 | 4.12 | 4.12 |
348.41 | 2.03 | 2.03 |
245.28 | 2.68 | 2.68 |
272.31 | 3.66 | 3.66 |
440.46 | 5.39 | 5.39 |
325.59 | 4.75 | 4.75 |
267.36 | 4.26 | 4.26 |
319.45 | 4.59 | 4.59 |
275.31 | 3.33 | 3.33 |
273.33 | 2.44 | 2.44 |
346.40 | 3.33 | 3.33 |
270.33 | 4.90 | 4.90 |
339.35 | 3.31 | 3.31 |
302.76 | 2.96 | 2.96 |
361.23 | 4.16 | 4.16 |
297.79 | 1.27 | 1.27 |
290.25 | 3.79 | 3.79 |
441.86 | 4.82 | 4.82 |
405.50 | 4.80 | 4.80 |
338.28 | 4.62 | 4.62 |
359.41 | 1.47 | 1.47 |
347.26 | 3.78 | 3.78 |
332.36 | 4.70 | 4.70 |
298.77 | 4.95 | 4.95 |
444.60 | 4.99 | 4.99 |
403.44 | 4.51 | 4.51 |
278.31 | 3.90 | 3.90 |
420.51 | 6.71 | 6.71 |
368.66 | 4.80 | 4.80 |
323.35 | 3.09 | 3.09 |
367.28 | 3.70 | 3.70 |
249.75 | 2.91 | 2.91 |
442.32 | 6.40 | 6.40 |
510.43 | 7.68 | 7.68 |
571.68 | 7.18 | 7.18 |
383.67 | 4.94 | 4.94 |
393.40 | 4.51 | 4.51 |
476.05 | 7.29 | 7.29 |
448.37 | 7.15 | 7.15 |
372.42 | 5.13 | 5.13 |
465.59 | 3.98 | 3.98 |
431.56 | 6.92 | 6.92 |
367.41 | 2.53 | 2.53 |
456.98 | 5.34 | 5.34 |
412.49 | 5.47 | 5.47 |
479.85 | 3.90 | 3.90 |
398.51 | 5.20 | 5.20 |
497.75 | 4.59 | 4.59 |
354.47 | 4.02 | 4.02 |
440.53 | 3.52 | 3.52 |
413.53 | 4.11 | 4.11 |
307.86 | 3.70 | 3.70 |
420.68 | 5.55 | 5.55 |
359.77 | 3.66 | 3.66 |
420.49 | 3.68 | 3.68 |
484.96 | 3.17 | 3.17 |
500.58 | 3.67 | 3.67 |
397.50 | 4.24 | 4.24 |
341.44 | 5.94 | 5.94 |
574.24 | 5.29 | 5.29 |
384.50 | 4.03 | 4.03 |
346.43 | 4.20 | 4.20 |
346.82 | 2.79 | 2.79 |
436.58 | 5.22 | 5.22 |
418.59 | 4.27 | 4.27 |
261.41 | 4.11 | 4.11 |
385.87 | 5.30 | 5.30 |
456.51 | 4.03 | 4.03 |
377.87 | 4.09 | 4.09 |
328.17 | 4.12 | 4.12 |
493.61 | 4.00 | 4.00 |
381.82 | 4.25 | 4.25 |
319.36 | 3.47 | 3.47 |
391.49 | 4.52 | 4.52 |
343.39 | 4.49 | 4.49 |
309.82 | 3.80 | 3.80 |
252.32 | 2.88 | 2.88 |
636.71 | 10.45 | 10.45 |
491.54 | 4.32 | 4.32 |
413.52 | 5.59 | 5.59 |
397.54 | 3.75 | 3.75 |
354.41 | 4.46 | 4.46 |
189.22 | 1.53 | 1.53 |
312.42 | 4.34 | 4.34 |
438.90 | 4.04 | 4.04 |
326.45 | 4.46 | 4.46 |
292.34 | 3.42 | 3.42 |
362.44 | 4.24 | 4.24 |
281.28 | 2.92 | 2.92 |
420.18 | 4.45 | 4.45 |
403.92 | 4.79 | 4.79 |
307.38 | 2.49 | 2.49 |
487.77 | 6.43 | 6.43 |
389.80 | 3.67 | 3.67 |
507.05 | 4.87 | 4.87 |
441.33 | 4.79 | 4.79 |
430.52 | 5.53 | 5.53 |
400.95 | 4.57 | 4.57 |
218.26 | 1.35 | 1.35 |
286.77 | 3.26 | 3.26 |
462.43 | 3.68 | 3.68 |
495.07 | 4.07 | 4.07 |
432.36 | 3.28 | 3.28 |
459.93 | 6.39 | 6.39 |
456.98 | 5.34 | 5.34 |
480.01 | 5.37 | 5.37 |
349.53 | 4.70 | 4.70 |
366.35 | 5.45 | 5.45 |
309.32 | 3.38 | 3.38 |
422.44 | 5.33 | 5.33 |
322.45 | 4.08 | 4.08 |
341.72 | 4.16 | 4.16 |
726.97 | 5.87 | 5.87 |
494.56 | 3.01 | 3.01 |
370.49 | 3.80 | 3.80 |
303.39 | 3.91 | 3.91 |
496.01 | 7.33 | 7.33 |
447.54 | 6.42 | 6.42 |
434.54 | 3.95 | 3.95 |
494.66 | 4.96 | 4.96 |
329.38 | 2.38 | 2.38 |
340.40 | 3.76 | 3.76 |
431.32 | 5.34 | 5.34 |
459.62 | 4.69 | 4.69 |
340.79 | 4.72 | 4.72 |
357.41 | 4.88 | 4.88 |
364.45 | 5.25 | 5.25 |
493.40 | 4.64 | 4.64 |
448.52 | 4.30 | 4.30 |
377.87 | 4.64 | 4.64 |
515.15 | 7.63 | 7.63 |
388.52 | 4.85 | 4.85 |
458.63 | 5.30 | 5.30 |
373.41 | 4.50 | 4.50 |
457.83 | 4.30 | 4.30 |
327.70 | 3.85 | 3.85 |
479.54 | 3.31 | 3.31 |
367.53 | 5.10 | 5.10 |
470.17 | 6.64 | 6.64 |
422.32 | 4.75 | 4.75 |
426.54 | 4.88 | 4.88 |
347.84 | 4.63 | 4.63 |
445.53 | 5.14 | 5.14 |
268.32 | 3.00 | 3.00 |
586.75 | 5.63 | 5.63 |
465.62 | 7.40 | 7.40 |
280.17 | 3.96 | 3.96 |
353.38 | 1.40 | 1.40 |
393.49 | 2.91 | 2.91 |
356.43 | 4.99 | 4.99 |
405.50 | 3.62 | 3.62 |
387.49 | 6.34 | 6.34 |
496.50 | 5.20 | 5.20 |
228.34 | 3.17 | 3.17 |
434.49 | 5.47 | 5.47 |
283.71 | 4.01 | 4.01 |
371.87 | 2.83 | 2.83 |
199.25 | 2.41 | 2.41 |
298.77 | 5.03 | 5.03 |
378.49 | 4.12 | 4.12 |
453.33 | 5.78 | 5.78 |
468.34 | 3.78 | 3.78 |
199.25 | 2.98 | 2.98 |
423.43 | 3.39 | 3.39 |
274.39 | 3.85 | 3.85 |
267.34 | 3.05 | 3.05 |
453.55 | 8.40 | 8.40 |
265.32 | 2.98 | 2.98 |
260.35 | 0.94 | 0.94 |
460.54 | 6.38 | 6.38 |
326.40 | 4.99 | 4.99 |
316.79 | 4.00 | 4.00 |
332.51 | 4.23 | 4.23 |
427.32 | 2.76 | 2.76 |
422.96 | 3.07 | 3.07 |
384.31 | 3.95 | 3.95 |
380.44 | 4.79 | 4.79 |
341.42 | 4.76 | 4.76 |
319.43 | 3.52 | 3.52 |
554.51 | 7.90 | 7.90 |
328.20 | 2.53 | 2.53 |
268.14 | 4.11 | 4.11 |
445.52 | 3.51 | 3.51 |
274.32 | 3.41 | 3.41 |
362.43 | 3.88 | 3.88 |
419.48 | 6.33 | 6.33 |
659.69 | 6.64 | 6.64 |
293.32 | 3.78 | 3.78 |
345.83 | 2.90 | 2.90 |
413.59 | 6.79 | 6.79 |
337.43 | 5.52 | 5.52 |
359.43 | 5.61 | 5.61 |
201.27 | 3.20 | 3.20 |
334.38 | 3.52 | 3.52 |
357.41 | 2.07 | 2.07 |
496.69 | 5.56 | 5.56 |
645.20 | 6.86 | 6.86 |
346.90 | 3.79 | 3.79 |
376.43 | 4.97 | 4.97 |
347.84 | 4.08 | 4.08 |
318.33 | 4.39 | 4.39 |
394.43 | 3.54 | 3.54 |
382.87 | 2.65 | 2.65 |
484.60 | 5.96 | 5.96 |
463.96 | 4.65 | 4.65 |
287.37 | 4.44 | 4.44 |
287.79 | 4.31 | 4.31 |
314.43 | 4.75 | 4.75 |
546.60 | 7.48 | 7.48 |
335.84 | 3.43 | 3.43 |
440.29 | 3.00 | 3.00 |
338.28 | 4.62 | 4.62 |
335.45 | 3.89 | 3.89 |
307.44 | 4.53 | 4.53 |
232.71 | 3.49 | 3.49 |
371.46 | 5.95 | 5.95 |
284.75 | 3.92 | 3.92 |
292.51 | 4.08 | 4.08 |
334.39 | 3.58 | 3.58 |
420.56 | 6.03 | 6.03 |
460.56 | 4.89 | 4.89 |
362.44 | 4.50 | 4.50 |
331.42 | 2.60 | 2.60 |
480.59 | 5.34 | 5.34 |
391.41 | 4.14 | 4.14 |
286.33 | 3.96 | 3.96 |
358.39 | 3.93 | 3.93 |
301.41 | 3.91 | 3.91 |
261.75 | 3.90 | 3.90 |
355.44 | 4.97 | 4.97 |
420.33 | 6.70 | 6.70 |
389.36 | 5.79 | 5.79 |
354.81 | 5.78 | 5.78 |
348.40 | 4.67 | 4.67 |
356.43 | 5.57 | 5.57 |
469.01 | 5.99 | 5.99 |
592.66 | 8.20 | 8.20 |
409.51 | 4.62 | 4.62 |
360.89 | 3.32 | 3.32 |
451.57 | 7.35 | 7.35 |
294.45 | 3.50 | 3.50 |
349.86 | 3.96 | 3.96 |
396.92 | 4.96 | 4.96 |
357.89 | 4.75 | 4.75 |
282.55 | 2.73 | 2.73 |
579.12 | 9.64 | 9.64 |
662.87 | 3.60 | 3.60 |
287.32 | 1.31 | 1.31 |
268.36 | 3.67 | 3.67 |
308.36 | 4.28 | 4.28 |
289.34 | 4.03 | 4.03 |
290.25 | 2.92 | 2.92 |
245.28 | 2.27 | 2.27 |
320.40 | 4.15 | 4.15 |
480.59 | 7.28 | 7.28 |
357.25 | 5.45 | 5.45 |
335.32 | 3.56 | 3.56 |
309.41 | 3.34 | 3.34 |
637.73 | 5.50 | 5.50 |
420.51 | 3.92 | 3.92 |
308.39 | 3.39 | 3.39 |
245.32 | 3.60 | 3.60 |
279.34 | 3.29 | 3.29 |
312.19 | 2.55 | 2.55 |
265.40 | 2.82 | 2.82 |
382.25 | 5.79 | 5.79 |
657.77 | 7.70 | 7.70 |
273.72 | 3.53 | 3.53 |
410.43 | 1.58 | 1.58 |
500.19 | 5.13 | 5.13 |
359.48 | 3.73 | 3.73 |
349.22 | 4.08 | 4.08 |
274.32 | 2.76 | 2.76 |
524.58 | 7.52 | 7.52 |
362.27 | 3.63 | 3.63 |
621.78 | 7.23 | 7.23 |
501.37 | 7.04 | 7.04 |
426.59 | 6.09 | 6.09 |
631.73 | 7.20 | 7.20 |
406.51 | 5.01 | 5.01 |
286.76 | 4.34 | 4.34 |
357.81 | 2.13 | 2.13 |
348.19 | 5.21 | 5.21 |
469.31 | 3.61 | 3.61 |
305.85 | 3.63 | 3.63 |
389.54 | 4.17 | 4.17 |
380.36 | 4.82 | 4.82 |
559.64 | 6.40 | 6.40 |
416.52 | 4.17 | 4.17 |
312.41 | 2.72 | 2.72 |
390.51 | 4.42 | 4.42 |
448.59 | 5.01 | 5.01 |
291.82 | 3.07 | 3.07 |
254.33 | 3.28 | 3.28 |
368.91 | 5.09 | 5.09 |
286.20 | 4.11 | 4.11 |
282.16 | 2.54 | 2.54 |
366.89 | 3.95 | 3.95 |
434.56 | 5.33 | 5.33 |
293.53 | 3.63 | 3.63 |
336.39 | 4.03 | 4.03 |
462.62 | 5.40 | 5.40 |
432.91 | 5.43 | 5.43 |
414.49 | 4.73 | 4.73 |
377.91 | 4.04 | 4.04 |
417.44 | 4.96 | 4.96 |
468.47 | 5.09 | 5.09 |
411.96 | 5.82 | 5.82 |
293.32 | 3.76 | 3.76 |
310.42 | 4.85 | 4.85 |
303.79 | 4.09 | 4.09 |
436.01 | 5.10 | 5.10 |
391.90 | 4.48 | 4.48 |
411.63 | 4.27 | 4.27 |
360.24 | 4.22 | 4.22 |
367.41 | 4.09 | 4.09 |
314.47 | 3.79 | 3.79 |
458.86 | 5.49 | 5.49 |
333.58 | 5.43 | 5.43 |
327.43 | 4.18 | 4.18 |
363.46 | 4.65 | 4.65 |
314.82 | 4.55 | 4.55 |
453.58 | 3.84 | 3.84 |
395.53 | 5.20 | 5.20 |
355.95 | 3.72 | 3.72 |
425.96 | 4.84 | 4.84 |
458.63 | 4.56 | 4.56 |
281.14 | 4.29 | 4.29 |
278.71 | 4.43 | 4.43 |
400.46 | 4.42 | 4.42 |
315.84 | 4.99 | 4.99 |
352.79 | 5.61 | 5.61 |
425.96 | 4.84 | 4.84 |
450.58 | 5.35 | 5.35 |
350.85 | 5.53 | 5.53 |
315.68 | 4.32 | 4.32 |
416.29 | 4.16 | 4.16 |
321.80 | 3.40 | 3.40 |
383.49 | 3.79 | 3.79 |
487.03 | 3.59 | 3.59 |
417.98 | 4.25 | 4.25 |
308.43 | 3.69 | 3.69 |
395.73 | 4.13 | 4.13 |
297.24 | 2.35 | 2.35 |
279.41 | 3.29 | 3.29 |
384.50 | 3.67 | 3.67 |
398.46 | 5.24 | 5.24 |
401.89 | 5.65 | 5.65 |
403.95 | 3.86 | 3.86 |
472.47 | 4.43 | 4.43 |
440.55 | 4.76 | 4.76 |
329.84 | 3.61 | 3.61 |
309.33 | 2.18 | 2.18 |
368.40 | 3.79 | 3.79 |
392.42 | 2.28 | 2.28 |
468.11 | 8.20 | 8.20 |
431.37 | 4.60 | 4.60 |
363.89 | 4.35 | 4.35 |
254.31 | 1.62 | 1.62 |
254.27 | 3.09 | 3.09 |
335.83 | 3.57 | 3.57 |
393.31 | 4.23 | 4.23 |
280.33 | 4.00 | 4.00 |
310.38 | 3.59 | 3.59 |
358.44 | 6.34 | 6.34 |
321.31 | 3.81 | 3.81 |
341.33 | 0.31 | 0.31 |
490.67 | 5.47 | 5.47 |
380.49 | 3.69 | 3.69 |
519.98 | 5.52 | 5.52 |
487.69 | 6.59 | 6.59 |
485.65 | 6.65 | 6.65 |
489.52 | 5.36 | 5.36 |
420.49 | 4.83 | 4.83 |
401.51 | 4.70 | 4.70 |
396.48 | 5.11 | 5.11 |
492.91 | 5.81 | 5.81 |
476.91 | 6.11 | 6.11 |
472.45 | 5.30 | 5.30 |
317.82 | 3.52 | 3.52 |
301.78 | 2.52 | 2.52 |
311.39 | 4.85 | 4.85 |
491.95 | 5.68 | 5.68 |
341.41 | 4.86 | 4.86 |
484.60 | 6.20 | 6.20 |
405.48 | 3.93 | 3.93 |
352.44 | 2.43 | 2.43 |
348.31 | 4.54 | 4.54 |
465.47 | 4.32 | 4.32 |
389.88 | 6.11 | 6.11 |
493.57 | 5.11 | 5.11 |
313.36 | 2.81 | 2.81 |