Basic Information
ID: ALA3361506
Type: Binding
Description: Inhibition of constitutively activated GST-tagged human MEK1 S218D/S22D (MEK1DD) mutant assessed blocking of increase in bovine MBP kinase activity of recombinant His6-tagged ERK2 using [gamma32P]ATP by liquid scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3361506
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 267.28 | 3.05 | 3.05 |
| 281.31 | 3.44 | 3.44 |
| 301.73 | 3.70 | 3.70 |
| 358.83 | 3.60 | 3.60 |
| 358.83 | 4.52 | 4.52 |
| 372.85 | 4.92 | 4.92 |
| 388.85 | 4.15 | 4.15 |
| 374.82 | 3.50 | 3.50 |
| 404.85 | 2.86 | 2.86 |
| 401.89 | 4.07 | 4.07 |
| 373.84 | 3.46 | 3.46 |
| 406.87 | 5.32 | 5.32 |
| 400.86 | 4.30 | 4.30 |
| 340.38 | 2.85 | 2.85 |
| 370.41 | 2.21 | 2.21 |