Basic Information
ID: ALA3361507
Type: Binding
Description: Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 mins by immunoblotting method
Organism: Rattus norvegicus
Cell type: C6
Activity Charts
Bioactivity
Activity Types for Assay ALA3361507
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 267.28 | 3.05 | 3.05 |
| 281.31 | 3.44 | 3.44 |
| 301.73 | 3.70 | 3.70 |
| 358.83 | 3.60 | 3.60 |
| 358.83 | 4.52 | 4.52 |
| 372.85 | 4.92 | 4.92 |
| 388.85 | 4.15 | 4.15 |
| 374.82 | 3.50 | 3.50 |
| 404.85 | 2.86 | 2.86 |
| 401.89 | 4.07 | 4.07 |
| 373.84 | 3.46 | 3.46 |
| 406.87 | 5.32 | 5.32 |
| 400.86 | 4.30 | 4.30 |
| 340.38 | 2.85 | 2.85 |
| 370.41 | 2.21 | 2.21 |