Basic Information
ID: ALA3361803
Type: Binding
Description: Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-[14C]arachidonyl-phosphatidylcholine liposomes substrate by scintillation counting
Organism: Homo sapiens
Cell type: U-937
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA3361803
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 746.16 | 9.77 | 9.77 |
| 355.44 | 5.24 | 5.24 |
| 369.46 | 5.43 | 5.43 |
| 383.49 | 5.74 | 5.74 |
| 508.59 | 5.57 | 5.57 |
| 525.05 | 6.09 | 6.09 |
| 520.63 | 5.44 | 5.44 |
| 520.63 | 5.44 | 5.44 |
| 550.65 | 5.45 | 5.45 |
| 384.48 | 4.85 | 4.85 |
| 393.49 | 4.95 | 4.95 |
| 393.49 | 4.71 | 4.71 |
| 368.48 | 4.83 | 4.83 |
| 421.46 | 6.48 | 6.48 |
| 367.45 | 5.51 | 5.51 |
| 371.44 | 4.88 | 4.88 |
| 506.60 | 5.27 | 5.27 |
| 385.46 | 5.27 | 5.27 |
| 490.60 | 5.43 | 5.43 |
| 383.49 | 5.49 | 5.49 |
| 385.46 | 5.14 | 5.14 |
| 385.46 | 5.14 | 5.14 |
| 385.46 | 5.14 | 5.14 |
| 520.63 | 5.44 | 5.44 |
| 534.65 | 5.83 | 5.83 |
| 427.54 | 6.22 | 6.22 |
| 427.54 | 6.22 | 6.22 |
| 550.65 | 4.80 | 4.80 |
| 556.61 | 6.03 | 6.03 |
| 574.60 | 6.33 | 6.33 |
| 582.70 | 7.23 | 7.23 |
| 504.63 | 5.74 | 5.74 |
| 525.05 | 6.09 | 6.09 |
| 387.45 | 5.57 | 5.57 |
| 335.77 | 4.50 | 4.50 |
| 263.30 | 3.73 | 3.73 |