Basic Information
ID: ALA3362371
Type: Binding
Description: Binding affinity to human GFP-tagged NPC1L1 L1072T/L1168I mutant expressed in HEK293 cells assessed as localization to plasma membrane at 10 uM after 24 hrs by fluorescence microscopic analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3362371
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 294.35 | 3.05 | 3.05 |
| 308.38 | 3.31 | 3.31 |
| 322.41 | 3.66 | 3.66 |
| 350.46 | 4.44 | 4.44 |
| 378.52 | 5.22 | 5.22 |
| 406.57 | 6.00 | 6.00 |
| 382.46 | 2.38 | 2.38 |
| 362.47 | 4.63 | 4.63 |
| 376.50 | 5.02 | 5.02 |
| 334.42 | 3.85 | 3.85 |
| 336.44 | 4.09 | 4.09 |
| 350.46 | 4.48 | 4.48 |
| 362.47 | 4.58 | 4.58 |
| 364.45 | 3.43 | 3.43 |
| 384.48 | 4.88 | 4.88 |
| 294.35 | 3.16 | 3.16 |
| 308.38 | 3.17 | 3.17 |
| 322.41 | 3.66 | 3.66 |
| 384.48 | 4.69 | 4.69 |
| 414.51 | 4.69 | 4.69 |
| 352.39 | 2.72 | 2.72 |
| 380.44 | 3.50 | 3.50 |
| 379.46 | 2.72 | 2.72 |
| 407.51 | 3.51 | 3.51 |
| 340.47 | 3.77 | 3.77 |
| 354.49 | 4.16 | 4.16 |
| 368.52 | 4.55 | 4.55 |
| 382.55 | 4.94 | 4.94 |
| 354.49 | 4.64 | 4.64 |
| 366.46 | 4.72 | 4.72 |
| 302.42 | 3.25 | 3.25 |
| 312.41 | 3.17 | 3.17 |
| 326.44 | 3.43 | 3.43 |
| 340.47 | 3.77 | 3.77 |
| 340.47 | 3.82 | 3.82 |
| 366.51 | 4.31 | 4.31 |
| 354.49 | 4.21 | 4.21 |
| 368.52 | 4.60 | 4.60 |
| 354.49 | 4.21 | 4.21 |
| 368.52 | 4.60 | 4.60 |
| 388.51 | 5.32 | 5.32 |
| 356.47 | 2.79 | 2.79 |
| 380.53 | 4.74 | 4.74 |
| 394.56 | 5.13 | 5.13 |
| 352.48 | 3.96 | 3.96 |
| 366.51 | 4.30 | 4.30 |
| 380.53 | 4.70 | 4.70 |
| 324.42 | 3.42 | 3.42 |
| 338.45 | 3.43 | 3.43 |
| 352.48 | 3.91 | 3.91 |
| 366.51 | 4.30 | 4.30 |
| 394.56 | 5.09 | 5.09 |
| 408.59 | 5.48 | 5.48 |
| 382.50 | 3.54 | 3.54 |
| 368.48 | 2.89 | 2.89 |
| 366.51 | 4.48 | 4.48 |
| 414.55 | 4.94 | 4.94 |