Basic Information
ID: ALA3363426
Type: Binding
Description: Antagonist activity against human TRPA1 expressed in T-REx HEK cells assessed as inhibition of AITC-induced increase in intracellular Ca2+ accumulation pre-incubated for 3 mins prior to AITC stimulation by Fluo-4 AM dye based fluorescence assay
Organism: Homo sapiens
Cell type: HEK
Activity Charts
Bioactivity
Activity Types for Assay ALA3363426
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.90 | 4.39 | 4.39 |
| 338.45 | 3.26 | 3.26 |
| 368.48 | 3.26 | 3.26 |
| 376.91 | 3.62 | 3.62 |
| 720.96 | 6.78 | 6.78 |
| 384.48 | 2.23 | 2.23 |
| 336.44 | 3.18 | 3.18 |
| 382.46 | 2.79 | 2.79 |
| 384.48 | 2.65 | 2.65 |
| 716.88 | 4.53 | 4.53 |
| 340.47 | 3.08 | 3.08 |
| 398.50 | 3.30 | 3.30 |
| 338.45 | 3.26 | 3.26 |