Basic Information
ID: ALA3363506
Type: Binding
Description: Inhibition of human MDM2 (1-188 aa) -p53 (1-83 aa) interaction expressed in Escherichia coli after 18 hrs by HTRF assay in presence of 15% human serum
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3363506
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 478.42 | 5.69 | 5.69 |
| 462.42 | 6.72 | 6.72 |
| 492.44 | 6.35 | 6.35 |
| 504.45 | 6.49 | 6.49 |
| 501.41 | 6.67 | 6.67 |
| 517.48 | 7.14 | 7.14 |
| 511.45 | 7.08 | 7.08 |
| 512.44 | 6.47 | 6.47 |
| 511.45 | 7.08 | 7.08 |
| 511.45 | 7.08 | 7.08 |
| 497.42 | 6.69 | 6.69 |
| 525.48 | 7.32 | 7.32 |
| 523.46 | 7.08 | 7.08 |
| 525.48 | 7.47 | 7.47 |
| 525.48 | 7.39 | 7.39 |
| 545.89 | 7.73 | 7.73 |
| 551.51 | 7.96 | 7.96 |
| 525.48 | 7.39 | 7.39 |
| 525.48 | 7.39 | 7.39 |
| 525.48 | 7.39 | 7.39 |
| 469.37 | 6.13 | 6.13 |
| 468.38 | 6.74 | 6.74 |
| 434.36 | 5.94 | 5.94 |