Basic Information
ID: ALA3364950
Type: Binding
Description: Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40 mins by Hoechst 33342 staining-based assay
Format: BAO_0000219
Organism: Mus musculus
Cell type: Hepatocyte
Target: Glucokinase(ALA3112387)
Document: ALA3352455
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40 mins by Hoechst 33342 staining-based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3364950
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 485.41 | 1.88 | 1.88 |
| 519.86 | 2.54 | 2.54 |
| 564.31 | 2.64 | 2.64 |
| 549.50 | 2.64 | 2.64 |
| 539.46 | 1.23 | 1.23 |
| 553.49 | 1.88 | 1.88 |
| 567.51 | 2.00 | 2.00 |
| 553.49 | 1.62 | 1.62 |
| 551.47 | 2.27 | 2.27 |
| 565.50 | 2.28 | 2.28 |
| 579.53 | 2.77 | 2.77 |
| 593.55 | 3.33 | 3.33 |
| 607.58 | 3.50 | 3.50 |
| 579.53 | 2.59 | 2.59 |
| 551.47 | 3.14 | 3.14 |
| 581.56 | 3.92 | 3.92 |
| 561.51 | 3.55 | 3.55 |
| 579.50 | 3.69 | 3.69 |
| 579.50 | 3.69 | 3.69 |
| 579.50 | 3.69 | 3.69 |
| 577.51 | 3.25 | 3.25 |
| 604.53 | 2.65 | 2.65 |
| 639.60 | 2.95 | 2.95 |
| 562.50 | 2.94 | 2.94 |
| 562.50 | 2.94 | 2.94 |
| 580.49 | 3.08 | 3.08 |
| 580.49 | 3.08 | 3.08 |
| 576.52 | 3.25 | 3.25 |
| 576.52 | 3.25 | 3.25 |
| 592.52 | 2.95 | 2.95 |
| 592.52 | 2.95 | 2.95 |
| 617.60 | 4.76 | 4.76 |
| 618.58 | 4.16 | 4.16 |
| 602.52 | 3.69 | 3.69 |
| 616.54 | 4.00 | 4.00 |
| 630.57 | 3.07 | 3.07 |
| 616.54 | 3.04 | 3.04 |
| 601.53 | 3.43 | 3.43 |
| 600.54 | 4.03 | 4.03 |
| 617.60 | 4.76 | 4.76 |