Basic Information
ID: ALA3365532
Type: Binding
Description: Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3365532
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 189.26 | 2.42 | 2.42 |
| 217.32 | 3.20 | 3.20 |
| 224.74 | 2.96 | 2.96 |
| 204.27 | 2.07 | 2.07 |
| 203.29 | 2.81 | 2.81 |
| 223.28 | 2.67 | 2.67 |
| 233.27 | 2.40 | 2.40 |
| 245.33 | 3.18 | 3.18 |
| 253.35 | 3.96 | 3.96 |
| 253.35 | 3.96 | 3.96 |
| 253.35 | 3.96 | 3.96 |
| 204.28 | 2.20 | 2.20 |
| 204.28 | 2.20 | 2.20 |
| 204.28 | 2.20 | 2.20 |
| 204.28 | 2.20 | 2.20 |
| 217.32 | 3.12 | 3.12 |
| 217.32 | 3.12 | 3.12 |
| 217.32 | 3.12 | 3.12 |
| 217.32 | 3.12 | 3.12 |
| 233.31 | 2.82 | 2.82 |
| 221.28 | 2.95 | 2.95 |
| 237.73 | 3.46 | 3.46 |
| 271.29 | 3.83 | 3.83 |
| 282.19 | 3.57 | 3.57 |
| 231.34 | 3.37 | 3.37 |
| 246.36 | 2.87 | 2.87 |
| 279.39 | 4.48 | 4.48 |
| 293.41 | 4.40 | 4.40 |
| 309.41 | 4.39 | 4.39 |
| 219.29 | 2.51 | 2.51 |
| 248.29 | 2.72 | 2.72 |
| 218.30 | 2.39 | 2.39 |
| 252.32 | 2.13 | 2.13 |