Basic Information
ID: ALA3365694
Type: Functional
Description: In vivo inhibition of HDAC in tumor of human HCT116 cells xenografted nu/nu mouse assessed as increase in histone hyperacetylation at 50 mg/kg, po after 4 to 12 hrs by immunoblotting method
Format: BAO_0000218
Organism: Homo sapiens
Cell type: HCT-116
Target: HCT-116(ALA394)
Document: ALA3352121
In vivo inhibition of HDAC in tumor of human HCT116 cells xenografted nu/nu mouse assessed as increase in histone hyperacetylation at 50 mg/kg, po after 4 to 12 hrs by immunoblotting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3365694
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 622.88 | 5.03 | 5.03 |
| 991.34 | 5.22 | 5.22 |
| 715.94 | 3.77 | 3.77 |